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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Prostaglandin reductase 1

glutathione reductase, pgr1, leukotriene B4 12-hydroxydehydrogenase, 15-Oxoprostaglandin 13-Reductase, PAM14, LTB4DH, prostaglandin reductase
This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009] (from NCBI)
Top mentioned proteins: catalase, SOD, ACID, CAN, GST
Papers using glutathione reductase antibodies
Role of apoptosis in atherosclerosis and its therapeutic implications
Supplier
Hamilton Karyn L. et al., In Oxidative Medicine and Cellular Longevity, 2003
... Heme oxygenase-1 (HO-1) antibody was from Affinity Bioreagents (Golden, CO), nitroquinone oxidoreductase (NQO1), and glutathione reductase (GR) antibodies, and appropriate HRP-conjugated secondary antibodies were purchased from AbCam, (Cambridge, MA) ...
Cerebral blood flow, the cerebrospinal fluid, and brain metabolism
Supplier
Chio Chung-Ching et al., In Journal of Biomedicine and Biotechnology, 1990
... were performed with a commercial glutathione peroxidase cellular activity assay kit (Oxis Research, Portland, USA) and a glutathione reductase assay kit (Oxis Research, Portland, USA), respectively ...
Papers on glutathione reductase
Alleviation of lead-induced physiological, metabolic, and ultramorphological changes in leaves of upland cotton through glutathione.
New
Zhu et al., Hangzhou, China. In Environ Sci Pollut Res Int, Feb 2016
Activities of antioxidant enzymes (catalase (CAT), superoxide dismutase (SOD), peroxidase (POD), glutathione reductase (GR), and ascorbate peroxidase (APX)) were also increased by GSH application under Pb toxicity.
Heat stress and antioxidant enzyme activity in bubaline (Bubalus bubalis) oocytes during in vitro maturation.
New
Upadhyay et al., Karnāl, India. In Int J Biometeorol, Feb 2016
Also, the antioxidant enzymatic activities of superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase were significantly (P < 0.05) increased in all the treatment groups compared to the control group.
Relationships among alcoholic liver disease, antioxidants, and antioxidant enzymes.
Review
New
Fukushima et al., Obihiro, Japan. In World J Gastroenterol, Feb 2016
Antioxidant phytochemicals, such as polyphenols, regulate the expression of ALD-associated proteins and peptides, namely, catalase, superoxide dismutase, glutathione, glutathione peroxidase, and glutathione reductase.
Nuclear selenoproteins and genome maintenance.
Review
New
Cheng et al., Wenzhou, China. In Iubmb Life, Jan 2016
To date, only five selenoproteins are experimentally demonstrated to reside in nucleus, exclusively or partially, including selenoprotein H, methionine-R-sulfoxide reductase 1, glutathione peroxidase-4, thioredoxin reductase-1, and thioredoxin glutathione reductase.
Strong Associations Exist among Oxidative Stress and Antioxidant Biomarkers in the Circulating, Cellular and Urinary Anatomical Compartments in Guatemalan Children from the Western Highlands.
New
Gil et al., Guatemala City, Guatemala. In Plos One, Dec 2015
The urinary oxidative stress biomarkers studied were F2-isoprostanes and 8-hydroxy-deoxy-guanosine. Red cell enzyme activities measured were: catalase, superoxide dismutase, glutathione peroxidase and glutathione reductase.
[Alleviation of salt stress during maize seed germination by presoaking with exogenous sugar].
New
Ma et al., In Ying Yong Sheng Tai Xue Bao, Sep 2015
Exogenous Glc and Suc presoaking could increase the activities of superoxide dismutase (SOD), ascorbate peroxidase (APX), glutathione peroxidase (GPX), glutathione reductase (GR) and induce glucose-6-phosphate dehydrogenase (G6PDH) activity of maize shoot under salt stress.
Interplay between cytosolic disulfide reductase systems and the Nrf2/Keap1 pathway.
Review
New
Schmidt, Bozeman, United States. In Biochem Soc Trans, Sep 2015
NADPH transfers reducing power from bioenergetic pathways to thioredoxin reductase-1 (TrxR1) and glutathione reductase (GR) to support essential reductive systems.
[Functional states of the antioxidant enzymatic complex of tissues of Mytilus galloprovincialis Lam. under conditions of oxidative stress].
Review
Golovina et al., In Zh Evol Biokhim Fiziol, 2014
It is shown that with increase of level of oxidative stress, a rise of activity of glutathione peroxidase (GP) and glutathione reductase (GR) is observed, as well as the rate of glutathione (GSH) in tissues also increases.
[Photodynamic reaction and oxidative stress - influence of the photodynamic effect on the activity antioxidant enzymes].
Review
Nowak-Stępniowska et al., In Postepy Biochem, 2013
An antioxidant protection of cell is formed by enzymes belonging to the family of oxidoreductases: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glutathione reductase (GR).
Antioxidant Potential of Plumieride against CCl₄-Induced Peroxidative Damage in Rats.
Gupta et al., Jaipur, India. In Antioxidants (basel), 2013
The antioxidant potential was evaluated by using hepatic tissue for SOD (superoxide dismutase), CAT (catalase), GSH (reduced glutathione), GPx (glutathione peroxidase), GR (glutathione reductase) and LPO (lipid peroxidation) alongwith the concomitant blood serum for AST & ALT (aspartate and alanine transaminases), GGT (gamma glutamyl transpeptidase), ALP (alkaline phosphatase), total bilirubin and total protein contents.
A set of genes associated with the interferon-γ response of lung cancer patients undergoing α-galactosylceramide-pulsed dendritic cell therapy.
GeneRIF
Nakayama et al., Chiba, Japan. In Cancer Sci, 2010
Data show that two genes, LTB4DH and DPYSL3, were confirmed to be candidate genes for the predictor of a good immune response.
Restoration of leukotriene B(4)-12-hydroxydehydrogenase/15- oxo-prostaglandin 13-reductase (LTBDH/PGR) expression inhibits lung cancer growth in vitro and in vivo.
GeneRIF
Tai et al., Lexington, United States. In Lung Cancer, 2010
restoration of expression in enzyme-negative lung cancer cell lines induces apoptosis and growth inhibition
Interaction of Sedlin with PAM14.
GeneRIF
Fan et al., Hefei, China. In J Cell Biochem, 2010
The results suggest that nucleus-localized Sedlin may play a role in regulation of transcriptional activities of the MRG family of transcription factors via binding to PAM14.
Identification of oxadiazoles as new drug leads for the control of schistosomiasis.
Impact
Williams et al., Normal, United States. In Nat Med, 2008
Phosphinic amides and oxadiazole 2-oxides, identified from a quantitative high-throughput screen, were shown to inhibit a parasite enzyme, thioredoxin glutathione reductase (TGR), with activities in the low micromolar to low nanomolar range.
Effects of decreased specific glutathione reductase activity in a chromate-tolerant mutant of Schizosaccharomyces pombe.
GeneRIF
Pesti et al., Pécs, Hungary. In Folia Microbiol (praha), 2007
Glutathione reductase activity is essential for chromate tolerance.
Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice.
Impact
Benjamin et al., Salt Lake City, United States. In Cell, 2007
The myopathic hearts show an increased recycling of oxidized glutathione (GSSG) to reduced glutathione (GSH), which is due to the augmented expression and enzymatic activities of glucose-6-phosphate dehydrogenase (G6PD), glutathione reductase, and glutathione peroxidase.
The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14.
GeneRIF
Ding et al., Shanghai, China. In Protein Sci, 2006
identify MRG15 residues that form a shallow hydrophobic pocket to interact with the N-terminal 50 residues of PAM14 through primarily hydrophobic interactions.
Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice.
Impact
Barlow et al., Los Angeles, United States. In Nature, 2006
To determine if two of the genes, glyoxalase 1 and glutathione reductase 1, have a causal role in the genesis of anxiety, we performed genetic manipulation using lentivirus-mediated gene transfer.
Conversion of a peroxiredoxin into a disulfide reductase by a triplet repeat expansion.
Impact
Beckwith et al., Boston, United States. In Science, 2001
An Escherichia coli strain that lacks both thioredoxin reductase and glutathione reductase grows extremely poorly.
Dehydrogenase Activities in Dystrophic Mice.
Impact
McCaman, In Science, 1960
The levels of activity of glucose-6-phosphate dehydrogenase, isocitric dehydrogenase, glutathione reductase, lactic dehydrogenase, and a-glycerophosphate dehydrogenase have been studied in the gastrocnemius muscle of mice with "dystrophia muscularis."
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