Asparaginase in the treatment of non-ALL hematologic malignancies.
Baltimore, United States. In Cancer Chemother Pharmacol, May 2014
Indeed, both Escherichia coli and Erwinia chrysanthemi asparaginases possess glutaminase enzymatic activity, and their administrations have shown to reduce serum glutamine level by deamidating glutamine to glutamate and ammonia.
Actinobacteriological research in India.
Taleigao, India. In Indian J Exp Biol, Aug 2013
Research on enzymes mostly covered lipases, amylases, proteases, endoglucanases, a-galactosidases, pectin lyases, xylanases, L-asparaginases, L-glutaminase and cellulases.
Cancer cell metabolism: implications for therapeutic targets.
Seoul, South Korea. In Exp Mol Med, 2012
In this review, we will discuss dysregulated and reprogrammed cancer metabolism followed by clinical relevance of the metabolic enzymes, such as hexokinase, phosphofructokinase, pyruvate kinase M2, lactate dehydrogenase, pyruvate dehydrogenase kinase and glutaminase.