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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Glycolipid transfer protein

GLTP, Glycolipid transfer protein
The protein encoded by this gene is similar to bovine and porcine proteins which accelerate transfer of certain glycosphingolipids and glyceroglycolipids between membranes. It is thought to be a cytoplasmic protein. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: ACID, CAN, Apo, V1a, fibrillin-1
Papers using GLTP antibodies
The glycolipid transfer protein interacts with the vesicle-associated membrane protein-associated protein VAP-A.
Supplier
Chammas Roger, In PLoS ONE, 2008
... The open reading frames (ORFs) for human GLTP (627 bp) and δ-catenin [full length (3675 bp), N-terminal region (2076 bp), or C-terminal region (1662 bp)] were cloned into pEGFP (Clontech) or pFLAG-CMV4 (Sigma) vector, ...
Papers on GLTP
Specificity of the mammalian glycolipid transfer proteins.
New
Mattjus, Turku, Finland. In Chem Phys Lipids, Jan 2016
Structurally the glycolipid transfer protein (GLTP) fold differs from other proteins that recognize glycolipids, such as non-specific lipid transfer proteins and lysosomal lipid degradation assisting proteins, even though they act on the same class of lipids.
Sphingolipid transfer proteins defined by the GLTP-fold.
New
Brown et al., Austin, United States. In Q Rev Biophys, Aug 2015
GLTPs and related homologs now are known to adopt a unique, helically dominated, two-layer 'sandwich' architecture defined as the GLTP-fold that provides the structural underpinning for the eukaryotic GLTP superfamily.
Proteomic screening and identification of microRNA-128 targets in glioma cells.
New
Peng et al., Beijing, China. In Proteomics, Aug 2015
A luciferase assay validated that 11 of 13 selected genes were potential targets of miR-128, and a mutagenesis experiment confirmed CBFB, CORO1C, GLTP, HnRNPF, and TROVE2 as the target genes.
Influence of membrane cholesterol in the molecular evolution and functional regulation of TRPV4.
New
Goswami et al., Bhubaneshwar, India. In Biochem Biophys Res Commun, Feb 2015
Synteny analysis confirms that TRPV4 has coevolved with two enzymes involved in sterol biosynthesis, namely MVK and GLTP.
Arabidopsis accelerated cell death 11, ACD11, is a ceramide-1-phosphate transfer protein and intermediary regulator of phytoceramide levels.
Brown et al., New York City, United States. In Cell Rep, 2014
A π helix (π bulge) near the lipid binding cleft distinguishes apo-ACD11 from other GLTP folds.
Membranes and mammalian glycolipid transferring proteins.
Review
Mattjus et al., Turku, Finland. In Chem Phys Lipids, 2014
Here we review the latest advances in the glycolipid transfer protein (GLTP) and the phosphoinositol 4-phosphate adaptor protein-2 (FAPP2) field, from a membrane point of view.
Alternation in the glycolipid transfer protein expression causes changes in the cellular lipidome.
Mattjus et al., Turku, Finland. In Plos One, 2013
The glycolipid transfer protein (GLTP) catalyzes the binding and transport of glycolipids, but not phospholipids or neutral lipids.
Structural insights into lipid-dependent reversible dimerization of human GLTP.
Malinina et al., Spain. In Acta Crystallogr D Biol Crystallogr, 2013
Human glycolipid transfer protein (hsGLTP) forms the prototypical GLTP fold and is characterized by a broad transfer selectivity for glycosphingolipids (GSLs).
GLTP mediated non-vesicular GM1 transport between native membranes.
Lang et al., Bonn, Germany. In Plos One, 2012
Using the soluble LTP glycolipid transfer protein (GLTP), we examined GM1 (monosialotetrahexosyl-ganglioside) transfer to native membrane surfaces.
Glycolipid transfer protein expression is affected by glycosphingolipid synthesis.
Mattjus et al., Turku, Finland. In Plos One, 2012
Members of the glycolipid transfer protein superfamily (GLTP) are found from animals and fungi to plants and red micro-alga.
Human glycolipid transfer protein gene (GLTP) expression is regulated by Sp1 and Sp3: involvement of the bioactive sphingolipid ceramide.
GeneRIF
Brown et al., Austin, United States. In J Biol Chem, 2011
This study represents the first characterization of any Gltp gene promoter and links human GLTP expression to sphingolipid homeostasis through ceramide
Human glycolipid transfer protein (GLTP) expression modulates cell shape.
GeneRIF
Brown et al., Austin, United States. In Plos One, 2010
findings represent the first known phenotypic changes triggered by GLTP overexpression and regulated by direct interaction with a p120-catenin protein family member
Human GLTP: Three distinct functions for the three tryptophans in a novel peripheral amphitropic fold.
GeneRIF
Brown et al., Austin, United States. In Biophys J, 2010
remarkable versatility for Trp, providing three distinct intramolecular functions in the novel amphitropic GLTP fold
The glycolipid transfer protein interacts with the vesicle-associated membrane protein-associated protein VAP-A.
GeneRIF
Mattjus et al., Turku, Finland. In Biochem Biophys Res Commun, 2009
GLTP and VAP-A were shown to interact.
Glycolipid acquisition by human glycolipid transfer protein dramatically alters intrinsic tryptophan fluorescence: insights into glycolipid binding affinity.
GeneRIF
Brown et al., Austin, United States. In J Biol Chem, 2009
Glycolipid acquisition by human glycolipid transfer protein dramatically alters intrinsic tryptophan fluorescence: insights into glycolipid binding affinity.
Glycolipid transfer proteins and membrane interaction.
Review
Mattjus, Turku, Finland. In Biochim Biophys Acta, 2009
The glycolipid transfer protein is found from animals and fungi to plants and red micro-alga.
Role of long-term potentiation of sympathetic ganglia (gLTP) in hypertension.
Review
Alzoubi et al., Houston, United States. In Clin Exp Hypertens, 2007
Ganglionic long-term potentiation (gLTP) is an activity-dependent sustained increase in the synaptic efficacy of the nicotinic pathway that has been demonstrated in autonomic ganglia.
Glycolipid transfer proteins.
Review
Mattjus et al., Austin, United States. In Biochim Biophys Acta, 2007
GLTP specificity encompasses both sphingoid- and glycerol-based glycolipids, but with a strict requirement that the initial sugar residue be beta-linked to the hydrophobic lipid backbone.
Structural basis for glycosphingolipid transfer specificity.
Impact
GeneRIF
Patel et al., New York City, United States. In Nature, 2004
crystal structures of apo-GLTP (1.65 A resolution) and lactosylceramide-bound (1.95 A) GLTP, in which the bound glycosphingolipid is sandwiched, after adaptive recognition, within a previously unknown two-layer all-alpha-helical topology
Glycolipid transfer protein and intracellular traffic of glucosylceramide.
Review
Sasaki, Sapporo, Japan. In Experientia, 1990
Glycolipid transfer protein (GL-TP), a nonglycosylated protein with a molecular weight of 22,000 K, has been purified from pig brain.
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