Expression pattern of the Hedgehog signaling pathway in pituitary adenomas.
Thessaloníki, Greece. In Neurosci Lett, 12 Feb 2016
We used a customized RT(2) Profiler PCR Array, to investigate the expression of genes related to Notch and Hedgehog signaling pathways (PTCH1, PTCH2, GLI1, GLI3, NOTCH3, JAG1, HES1, and HIP).
Aberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and Chemoresistance.
Mobile, United States. In Cancers (basel), 2014
The canonical hedgehog (HH) pathway is a multicomponent signaling cascade (HH, protein patched homolog 1 (PTCH1), smoothened (SMO)) that plays a pivotal role during embryonic development through activation of downstream effector molecules, namely glioma-associated oncogene homolog 1 (GLI1), GLI2 and GLI3.