Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochoremore suppliers
In The Journal of Cell Biology, 2003
... Giet, University of Rennes, Rennes, France), rat anti–α-tubulin (1:150; Serotec), mouse anti–CENP-A (1:2,000; Abcam), rabbit anti-DIC (1:500; provided ...
Chemical shift assignments of a new folded domain from yeast Pcf11.
Pessac, France. In Biomol Nmr Assign, 02 Aug 2015
Pcf11 interacts with RNA and the C-terminal domain (CTD) of the largest subunit of RNA polymerase II via the CTD-interaction domain (CID), and other peptide regions mediate contacts with CF IA subunits Clp1 and Rna14/Rna15.
The role of hedgehog signalling in skeletal health and disease.
Durham, United States. In Nat Rev Rheumatol, 16 Jul 2015
UNASSIGNED: Hedgehog ligands bind to protein patched homologue 1 (PTC), a conserved receptor that activates the GLI family of transcription factors, which are involved in development, disease and skeletal repair processes.
Targeting GLI factors to inhibit the Hedgehog pathway.
More papers using
Roma, Italy. In Trends Pharmacol Sci, 10 Jul 2015
Recently, particular interest has been elicited by the identification of molecules able to hit glioma-associated oncogene (GLI) factors, the final effectors of the Hh pathway, which provide a valid tool to overcome anti-SMO resistance.