Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochoremore suppliers
In The Journal of Cell Biology, 2003
... Giet, University of Rennes, Rennes, France), rat anti–α-tubulin (1:150; Serotec), mouse anti–CENP-A (1:2,000; Abcam), rabbit anti-DIC (1:500; provided ...
Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry.
Utrecht, Netherlands. In Nat Methods, 28 Oct 2015
Our approach is based on the application of mass spectrometry (MS)-cleavable cross-linkers, sequential collision-induced dissociation (CID)-tandem MS (MS/MS) and electron-transfer dissociation (ETD)-MS/MS acquisitions, and a dedicated search engine, XlinkX, which allows rapid cross-link identification against a complete human proteome database.
Chromatin Dynamics in Vivo: A Game of Musical Chairs.
Bethesda, United States. In Genes (basel), Dec 2014
Histones are a major component of chromatin, the nucleoprotein complex fundamental to regulating transcription, facilitating cell division, and maintaining genome integrity in almost all eukaryotes.
Hedgehog Signaling in Malignant Pleural Mesothelioma.
More papers using
Zürich, Switzerland. In Genes (basel), Dec 2014
Drugs inhibiting the pathway at the level of the smoothened receptor (Smo) or glioma-associated protein transcription factors (Gli) have been used mostly in experimental models.