Regulation of gut hormone secretion. Studies using isolated perfused intestines.
Copenhagen, Denmark. In Peptides, Sep 2015
UNASSIGNED: The incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are secreted from enteroendocrine cells in the intestine along with other gut hormones (PYY, CCK and neurotensin) shown to affect metabolism and/or appetite.
DPP4 in Diabetes.
Düsseldorf, Germany. In Front Immunol, 2014
Since the incretin hormones, glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide (GIP), are major regulators of post-prandial insulin secretion, inhibition of DPP4 by the gliptin family of drugs has gained considerable interest for the therapy of type 2 diabetic patients.
Pharmacology, physiology, and mechanisms of incretin hormone action.
Toronto, Canada. In Cell Metab, 2013
Incretin peptides, principally GLP-1 and GIP, regulate islet hormone secretion, glucose concentrations, lipid metabolism, gut motility, appetite and body weight, and immune function, providing a scientific basis for utilizing incretin-based therapies in the treatment of type 2 diabetes.