Roles for gliotransmission in the nervous system
In The Journal of Cell Biology, 2004
... anti-EEA1 mAb’s were purchased from BD; anti-TfR mAb was obtained from Invitrogen; anti-VAMP3 rabbit and anti-Iba1 goat pAb’s were obtained from Abcam; horseradish peroxidase–conjugated goat anti–mouse ... Clades of Adeno-associated viruses are widely disseminated in human tissues
In Molecular Therapy, 2003
... (1:500; Invitrogen), goat-anti-ChAT (1:100; Millipore, Billerica, MA), guinea-pig-anti-GFAP (1:1,000; Advanced Immunochemical, Long Beach, CA) and rabbit-anti-Iba1 (1:500; Dako, Carpentaria, CA) ...
Cross-signaling in metabotropic glutamate 2 and serotonin 2A receptor heteromers in mammalian cells.
Richmond, United States. In Pflugers Arch, Feb 2016
UNASSIGNED: We previously reported that co-expression of the Gi-coupled metabotropic glutamate receptor 2 (mGlu2R) and the Gq-coupled serotonin (5-HT) 2A receptor (2AR) in Xenopus oocytes (Fribourg et al. Cell 147:1011-1023, 2011) results in inverse cross-signaling, where for either receptor, strong agonists suppress and inverse agonists potentiate the signaling of the partner receptor.
New development in studies of formyl-peptide receptors: critical roles in host defense.
Shanghai, China. In J Leukoc Biol, Jan 2016
UNASSIGNED: Formyl-peptide receptors are a family of 7 transmembrane domain, Gi-protein-coupled receptors that possess multiple functions in many pathophysiologic processes because of their expression in a variety of cell types and their capacity to interact with a variety of structurally diverse, chemotactic ligands.
Anticancer effect of adenosine on gastric cancer via diverse signaling pathways.
Nishinomiya, Japan. In World J Gastroenterol, Nov 2015
Secondly, the A3 adenosine receptor, linked to Gi/Gq proteins, mediates apoptosis by activating the Gq protein effector, phospholipase Cγ, to produce inositol 1,4,5-trisphosphate and diacylglycerol, which activate protein kinase C. Consequently, the mechanisms underlying adenosine-induced apoptosis vary, depending upon gastric cancer cell types.