Blood-Borne Revitalization of the Aged Brain.
Palo Alto, United States. In Jama Neurol, Oct 2015
The age-associated plasma chemokine CCL11 has been shown to impair young brain function while GDF11 has been reported to increase the generation of neurons in aged mice.
GDF11 and the Mythical Fountain of Youth.
Ottawa, Canada. In Cell Metab, Aug 2015
(2015) re-investigate the activity of GDF11 in myogenesis, recently suggested as an anti-aging agent, and instead find a potent inhibitory effect on skeletal muscle regeneration.
The aging human recipient of transfusion products.
Bern, Switzerland. In Transfus Apher Sci, Jun 2015
Components of blood plasma, such as the growth-differentiation protein GDF11, were shown to enhance neurogenesis and to improve the vasculature in the animal cortex and to rejuvenate muscle tissue.
Rejuvenation: it's in our blood.
Seattle, United States. In Cell Metab, 2014
Recent studies report that rejuvenating effects of young blood extend to multiple tissues and have identified GDF11 and CCL11 as factors mediating these effects.