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GC-rich sequence DNA-binding factor 1

GC-rich sequence DNA-binding factor candidate GCFC, C21orf66, GCFC
This gene encodes a protein that may bind to GC-rich DNA sequences, which suggests its involvement in the regulation of transcription. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2009] (from NCBI)
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Papers on GC-rich sequence DNA-binding factor candidate GCFC
Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters.
Yaspo et al., Berlin, Germany. In Nucleic Acids Res, 2010
The GCFC1/C21orf66 distal promoter contains an inhibitory cis-regulatory element that is responsive to Trichostatin A (TSA) treatment according to promoter reporter assays in HEK 293 cells.
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