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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Gastrulation brain homeobox 1

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Top mentioned proteins: Gbx2, Otx2, PAX2, Wnt1, CAN
Papers on gbx1
Cerebellar development in the absence of Gbx function in zebrafish.
Moens et al., Seattle, United States. In Dev Biol, 2014
Using zebrafish mutants we show here that in the zebrafish gbx1 and gbx2 are required redundantly for morphogenesis of the cerebellar primordium and subsequent cerebellar differentiation, but that this requirement is alleviated by knocking down Otx.
Real-time PCR quantification of gene expression in embryonic mouse tissue.
Waters et al., Columbia, United States. In Methods Mol Biol, 2013
The Gbx family of transcription factors consists of two closely related proteins GBX1 and GBX2.
Evolutionarily conserved function of Gbx2 in anterior hindbrain development.
Waters et al., Columbia, United States. In Dev Dyn, 2011
In contrast, studies in zebrafish have implicated gbx1 in establishment of the MHB.
Zebrafish gbx1 refines the midbrain-hindbrain boundary border and mediates the Wnt8 posteriorization signal.
Brand et al., Dresden, Germany. In Neural Dev, 2008
In addition to its role in midbrain-hindbrain formation, we have shown that gbx1 is a novel mediator of Wnt8 signaling during hindbrain patterning.
Identification of a set of genes showing regionally enriched expression in the mouse brain.
Jones et al., Vancouver, Canada. In Bmc Neurosci, 2007
Data show that Gbx1 is regionally enriched in the Basal Nucleus of Meynert of mouse brain.
Three enhancer regions regulate gbx2 gene expression in the isthmic region during zebrafish development.
Yamasu et al., Saitama, Japan. In Mech Dev, 2006
In zebrafish, sequential expression of gbx1 and gbx2 in the anterior hindbrain contributes to this process, whereas in mouse embryos, a single Gbx gene (Gbx2) is responsible for MHB development.
cDNA cloning and expression of the human NOBOX gene in oocytes and ovarian follicles.
Picton et al., Leeds, United Kingdom. In Mol Hum Reprod, 2006
Study reveals the preferential expression of GBX1 by germinal vesicle (GV) oocytes.
The homeodomain transcription factor Gbx1 identifies a subpopulation of late-born GABAergic interneurons in the developing dorsal spinal cord.
Britsch et al., Berlin, Germany. In Dev Dyn, 2005
expression of Gbx1 suggests that it controls development of a specific subset of GABAergic neurons in the dorsal horn of the spinal cord
Positioning of the midbrain-hindbrain boundary organizer through global posteriorization of the neuroectoderm mediated by Wnt8 signaling.
Brand et al., Dresden, Germany. In Development, 2005
Wnt8 is required for the initial subdivision of the neuroectoderm, including onset of posterior gbx1 expression and establishment of the posterior border of otx2 expression.
Activation of HLXB9 by juxtaposition with MYB via formation of t(6;7)(q23;q36) in an AML-M4 cell line (GDM-1).
MacLeod et al., Braunschweig, Germany. In Genes Chromosomes Cancer, 2005
Using RT-PCR, we screened members of the EHG family of homeobox genes, comprising EN1 (at 2q14), GBX2 (at 2q36), and EN2, GBX1, and HLXB9 (at 7q36), for dysregulation in acute myeloid leukemia (AML) cell lines indicated by chromosomal breakpoints at these sites.
Isolation and expression of the homeobox gene Gbx1 during mouse development.
Brand et al., Dresden, Germany. In Dev Dyn, 2004
sequence and expression pattern of Gbx1 in mouse
gbx2 Homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain.
Yamasu et al., Saitama, Japan. In Dev Dyn, 2003
We also suggest that other factors, including gbx1, is required for the establishment of the MHB during gastrulation.
Cloning, expression and relationship of zebrafish gbx1 and gbx2 genes to Fgf signaling.
Brand et al., Dresden, Germany. In Mech Dev, 2003
Here we report the isolation, mapping, chromosomal synteny and spatiotemporal expression of gbx1 and gbx2 in zebrafish. We focus in particular on the expression of these genes during development of the midbrain-hindbrain territory.
Spiel-ohne-grenzen/pou2 mediates regional competence to respond to Fgf8 during zebrafish early neural development.
Brand et al., Dresden, Germany. In Development, 2002
By contrast, regional definition of the future MHB in the neuroectoderm by complementary expression of otx2 and gbx1, before the establishment of the complex regulatory cascade at the MHB, is normal in spg embryos.
spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer.
Driever et al., Freiburg, Germany. In Development, 2001
In spg mutants, despite apparently normal expression of otx2, gbx1 and fgf8 during late gastrula stages, the initial expression of pax2.1, wnt1 and eng2, as well as later expression of fgf8 in the MHB primordium are reduced.
Increase in expression of the homeobox gene, GBX1, in retinol-induced epidermal mucous metaplasia.
Hirano et al., Japan. In Biochem Biophys Res Commun, 2001
Using a degenerate RT-PCR-based screening method, we isolated the homeobox gene, Gbx1, from the shank skin of 13-day-old chick embryos.
Down-regulation of homeobox gene GBX2 expression inhibits human prostate cancer clonogenic ability and tumorigenicity.
Isaacs et al., Baltimore, United States. In Cancer Res, 1998
Previously, we have demonstrated that GBX genes, a homeobox-containing human family of DNA-binding transcription factors consisting of GBX1 and GBX2, are overexpressed in a panel of human prostatic cancer cell lines (ie., TSU-pr1, PC3, DU145, and LNCaP) compared to normal prostate.
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