Identification of Gender-Specific Genetic Variants in Patients With Bicuspid Aortic Valve.
Québec, Canada. In Am J Cardiol, Mar 2016
Nine genes previously associated with BAV (NOTCH1, AXIN1, EGFR, ENG, GATA5, NKX2-5, NOS3, PDIA2, and TGFBR2) were sequenced in 48 patients with BAV using the Ion Torrent Personal Genome Machine.
Discovery of signature genes in gastric cancer associated with prognosis.
In Neoplasma, Feb 2016
A total of 17 genes were identified as signature genes, such as DAB2, ALDH2, CD58, CITED2, BNIP3L, SLC43A2, FAU and COL5A1.Many signature genes associated with prognosis of GC were identified in present study, some of which have been implicated in the pathogenesis of GC.
Molecular biology of endometriosis: from aromatase to genomic abnormalities.
Chicago, United States. In Semin Reprod Med, May 2015
Defective CpG methylation affecting several genes that encode key transcription factors such as GATA6, steroidogenic factor-1, and estrogen receptor-β in endometriosis gives rise to overproduction of local estrogen and prostaglandins and suppression of progesterone receptor.
Hopping between differentiation states in lung adenocarcinoma.
Boston, United States. In Cancer Cell, 2013
The work by Cheung and colleagues, in this issue of Cancer Cell, demonstrates another example of how lineage-specific transcriptional regulators of differentiation, GATA6 and HOPX, can control the fate of lung adenocarcinoma progression.
15-lipoxygenase-1 in colorectal cancer: a review.
Nuneaton, United Kingdom. In Tumour Biol, 2008
Regulation of 15-LOX-1 expression is achieved at transcription level by global histone acetylation and may also be dependent on GATA-6, IL-4 and IL-13.