Lipid digestion and absorption in early life: an update.
Umeå, Sweden. In Curr Opin Clin Nutr Metab Care, 2010
Instead the PTL-related protein 2 and bile salt-stimulated lipase (BSSL) are the key enzymes secreted from pancreas, which in concerted action with gastric lipase operate to achieve efficient fat absorption during infancy.
Putting the brakes on dietary fat breakdown.
Göttingen, Germany. In Cell Metab, 2009
A Drosophila study (Sieber and Thummel, 2009 [this issue of Cell Metabolism]) now demonstrates that the orphan nuclear receptor DHR96 adjusts fat storage in flies by tuning gastric lipase expression.
Orlistat-associated adverse effects and drug interactions: a critical review.
Ioánnina, Greece. In Drug Saf, 2007
Interestingly, the use of orlistat has been associated with rare cases of acute kidney injury, possibly due to the increased fat malabsorption resulting from the inhibition of pancreatic and gastric lipase by orlistat, leading to the formation of soaps with calcium and resulting in increased free oxalate absorption and enteric hyperoxaluria.