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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Galanin receptor 3

GalR3, galanin receptor 3
binds galanin; mediates activation of GIRK1 and GIRK4 channel inward K+ currents; may play a role in neurotransmitter release [RGD, Feb 2006] (from NCBI)
Papers on GalR3
Galanin receptor 3--a potential target for acute pancreatitis therapy.
GeneRIF
Saccone et al., Adelaide, Australia. In Neurogastroenterol Motil, 2011
Data show that galanin receptor mRNA and protein are expressed in mouse pancreas, with GALR3 mRNA predominating.
Effects of intracerebroventricular galanin or a galanin receptor 2/3 agonist on the lesion induced by transient occlusion of the middle cerebral artery in female rats.
GeneRIF
Theodorsson et al., Linköping, Sweden. In Neuropeptides, 2011
Data show that a galanin or a galanin receptor R2/3 agonist doubles the size of the ischemic lesion following middle cerebral artery occlusion in rats.
Determining receptor-ligand interaction of human galanin receptor type 3.
GeneRIF
Langel et al., Stockholm, Sweden. In Neurochem Int, 2010
Mutated human GalR3 receptors are tested with competitive binding analysis in vitro, identifying six different sites in GalR3 that determine binding to galanin.
Evidence that the modulatory effect of galanin on inflammatory edema formation is mediated by the galanin receptor 3 in the murine microvasculature.
GeneRIF
Brain et al., Salzburg, Austria. In J Mol Neurosci, 2009
GalR3 is the receptor subtype mediating galanin's effects on the dermal microvasculature
Alcoholism is associated with GALR3 but not two other galanin receptor genes.
GeneRIF
Enoch et al., Bethesda, United States. In Genes Brain Behav, 2007
GALR3 showed a significant association with alcoholism that was driven by one SNP (rs3,091,367).
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