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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Galanin-like peptide

Galp, Galanin-like peptide
This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, may have vasoactive properties and serve as a marker for neuroblastic tumors.[provided by RefSeq, Mar 2009] (from NCBI)
Top mentioned proteins: ACID, CAN, HAD, V1a, fibrillin-1
Papers on Galp
Purification and characterization of a novel polysaccharide-peptide complex from Clinacanthus nutans Lindau leaves.
Sun et al., Zhenjiang, China. In Carbohydr Polym, Mar 2016
Methylation analysis, FT-IR, and (1)H NMR spectroscopy analysis revealed that CNP-1-2 might have a backbone consisting of 1,4-linked Glcp, 1,3-linked Glcp, 1,3-linked Manp, 1,4-linked Galp, 1,2,6-linked Galp and 1,2,6-linked Galp.
Site-specific integration and constitutive expression of key genes into Escherichia coli chromosome increases shikimic acid yields.
Zhu et al., Shanghai, China. In Enzyme Microb Technol, Jan 2016
Herein, crucial genes aroG, aroB, tktA, aroE (encoding 3-deoxy-d-arabinoheptulosonate-7-phosphate synthase, dehydroquinate synthase, transketolase and shikimate dehydrogenase, respectively) of SA pathway and glk, galP (encoding glucokinase and galactose permease) were integrated into the locus of ptsHIcrr (phosphoenolpyruvate: carbohydrate phosphotransferase system operon) in a shikimate kinase genetic defect strain Escherichia coli BW25113 (ΔaroL/aroK, DE3).
Mechanism-based candidate inhibitors of uridine diphosphate galactopyranose mutase (UGM).
Pinto et al., Saskatoon, Canada. In Carbohydr Res, Jan 2016
Uridine diphosphate-galactopyranose mutase (UGM), an enzyme found in many eukaryotic and prokaryotic human pathogens, catalyzes the interconversion of UDP-galactopyranose (UDP-Galp) and UDP-galactofuranose (UDP-Galf), the latter being used as the biosynthetic precursor of the galactofuranose polymer portion of the mycobacterium cell wall.
Antitumor and immunomodulatory activity of a water-soluble polysaccharide from Grifola frondosa.
Wu et al., Zhenjiang, China. In Carbohydr Polym, Jan 2016
The results revealed that GP11 was composed of → 1)-D-Manp-(6 →,→ 1)-D-Glcp-(4 →,→ 1)-D-Galp-(6 → and → 2,3,6)-D-Glcp-(1 →, with branches attached at O-2,3 of 1,2,3,6-linked Glcp residues and terminal T-Glcp.
Chemical characterization and in vitro antitumor activity of a single-component polysaccharide from Taxus chinensis var. mairei.
Yang et al., Hangzhou, China. In Carbohydr Polym, Dec 2015
It had a backbone composed of α-(1→3) Araf, α-(1→5) Araf and α-(1→4) Galp with branches composed of α-(1→3,5) Araf and β-(1→3,6) Manp.
Synthesis of a Conjugation-Ready, Phosphorylated, Tetrasaccharide Fragment of the O-PS of Vibrio cholerae O139.
Kováč et al., Bethesda, United States. In J Org Chem, Dec 2015
A new pathway to the tetrasaccharide α-Colp-(1→2)-4,6-P-β-d-Galp-(1→3)-[α-Colp-(1→4)]-β-d-GlcpNAc-1-(OCH2CH2)3NH2 has been developed.
Structural determination of the K14 capsular polysaccharide from an ST25 Acinetobacter baumannii isolate, D46.
De Castro et al., Sydney, Australia. In Carbohydr Res, Dec 2015
The structure was resolved on the basis of NMR spectroscopy and chemical analyses, and was found to contain a branched neutral pentasaccharide with a backbone composed of GalpNAc and Galp residues, all d configured, and a d-Glcp side group.
Structure and gene cluster of the O-antigen of Escherichia coli O165 containing 5-N-acetyl-7-N-[(R)-3-hydroxybutanoyl]pseudaminic acid.
Knirel et al., Moscow, Russia. In Glycobiology, Dec 2015
Analysis of the resulting linear tetrasaccharide and alkali-treated lipopolysaccharide by (1)H/(13)C 1D and 2D nuclear magnetic resonance spectroscopy enabled elucidation of the following structure of the O-polysaccharide: →8)-α-Psep5Hb7Ac-(2 → 6)-β-d-Galp-(1 → 4)-β-d-Glсp-(1 → 3)-α-d-GlсpNAc-(1→.
Frost Grape Polysaccharide (FGP), an Emulsion-Forming Arabinogalactan Gum from the Stems of Native North American Grape Species Vitis riparia Michx.
Vaughn et al., Peoria, United States. In J Agric Food Chem, Sep 2015
The sugar composition consists of l-arabinofuranose (l-Araf, 55.2%) and d-galactopyranose (d-Galp 30.1%), with smaller components of d-xylose (11.2%), d-mannose (3.5%), and glucuronic acid (GlcA, ∼2%), the latter linked via a galactosyl residue.
[Galanin-like peptide (GALP): localization, receptors and biological function].
Ciosek et al., Laizhou, China. In Postepy Hig Med Dosw (online), 2014
Galanin-like peptide (GALP) was isolated from porcine hypothalamus in 1999 on the basis of its ability to activate galanin receptors in vitro.
Endogenous peptides as risk markers to assess the development of insulin resistance.
Zhang et al., Yangzhou, China. In Peptides, 2014
Recent studies have provided compelling clues about some peptides and proteins, including galanin, galanin-like peptide, ghrelin, adiponectin, retinol binding protein 4 (RBP4) and CRP, which may be used to simplify and to improve the determination of insulin resistance.
Targeting UDP-galactopyranose mutases from eukaryotic human pathogens.
Sobrado et al., Blacksburg, United States. In Curr Pharm Des, 2012
UDP-Galactopyranose mutase (UGM) is a unique flavin-dependent enzyme that catalyzes the conversion of UDP-galactopyranose(UDP-Galp) to UDP-galactofuranose (UDP-Galf).
Neuronal circuits involving neuropeptide Y in hypothalamic arcuate nucleus-mediated feeding regulation.
Shioda et al., Kiryū, Japan. In Neuropeptides, 2012
Accumulated evidence shows that hypothalamic neuropeptides such as ghrelin, orexin, melanin-concentrating hormone (MCH), galanin-like peptide (GALP) and proopiomelanocortin (POMC) are involved in the regulation of feeding behavior and energy homeostasis via neuronal circuits in the hypothalamus.
Current knowledge of the Escherichia coli phosphoenolpyruvate-carbohydrate phosphotransferase system: peculiarities of regulation and impact on growth and product formation.
Bolívar et al., Ecatepec, Mexico. In Appl Microbiol Biotechnol, 2012
We discuss three main approaches applied efficiently to avoid these constraints resulting in obtaining PTS(-) glc(+) mutants useful for production purposes: (1) adaptive selection in chemostat culture system of PTS(-) mutants, resulting in the selection of strains that recovered the ability to grow in glucose, along with the simultaneous consumption of two carbon sources and reduced acetate production; (2) replacement in PTS(-) strains of the native GalP promoter by strong promoters or the substitution of this permease by recombinant glucose transport system; and (3) enhancement of Crp (crp+) in mgsA, pgi, and ptsG mutants, resulting in derivative strains that abolished CCR, allowing the simultaneous consumption of mixtures of sugars with low acetate production.
Unfolding free energy of a two-domain transmembrane sugar transport protein.
Booth et al., Bristol, United Kingdom. In Proc Natl Acad Sci U S A, 2010
Unfolding free energy of a two-domain transmembrane sugar transport protein, GalP.
The prototypical H+/galactose symporter GalP assembles into functional trimers.
Gonen et al., Seattle, United States. In J Mol Biol, 2010
Each monomer in the trimer forms its own channel, but an additional cavity (10 approximately 15 A in diameter) is apparent at the 3-fold axis of the oligomer.
Galanin-like peptide stimulates feeding and sexual behavior via dopaminergic fibers within the medial preoptic area of adult male rats.
Fraley et al., Holland, United States. In J Chem Neuroanat, 2009
These data suggest that GALP activates feeding and sexual behaviors in male rats by stimulating dopaminergic neurons that terminate within the mPOA.
Repression of galP, the galactose transporter in Escherichia coli, requires the specific regulator of N-acetylglucosamine metabolism.
Plumbridge et al., Paris, France. In Mol Microbiol, 2009
galP is repressed by a combination of NagC, GalR and GalS.
Relative substrate affinities of wild-type and mutant forms of the Escherichia coli sugar transporter GalP determined by solid-state NMR.
Middleton et al., Leeds, United Kingdom. In Mol Membr Biol, 2008
effects of the galP mutations W56F, W239F, R316W, T336Y and W434F on glucose binding
Structure of carbohydrate part of receptor on human uroepithelial cells for pyelonephritogenic Escherichia coli.
Winberg et al., In Lancet, 1981
The binding of pyelonephritogenic E. coli to urinary epithelial cells of P1 phenotypes was blocked by the synthetic disaccharide alpha-D-Galp-(1 leads to 4)-beta-D-Galp whose structures is related to that of the P blood group antigens.
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