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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Lectin, galactoside-binding, soluble, 7

galectin-7
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: galectin-1, galectin-3, p53, CAN, fibrillin-1
Papers on galectin-7
Galectin-7 Regulates Keratinocyte Proliferation and Differentiation through JNK-miR-203-p63 Signaling.
New
Liu et al., Taipei, Taiwan. In J Invest Dermatol, Jan 2016
Galectin-7, a member of the β-galactoside-binding protein family, is primarily expressed in stratified epithelial cells, including keratinocytes.
Pattern of galectins expression in actinic cheilitis with different risks of malignant transformation.
New
da Silveira et al., Natal, Brazil. In J Oral Pathol Med, Jan 2016
METHODS: Immunoexpression of galectin-1, galectin-3, galectin-7, and galectin-9 was semiquantitatively analyzed in 65 cases of actinic cheilitis graded as low risk (n = 40) or high risk (n = 25) of malignant transformation.
Design of a peptidic inhibitor that targets the dimer interface of a prototypic galectin.
New
St-Pierre et al., Québec, Canada. In Oncotarget, Jan 2016
Here, we report a new class of galectin inhibitors that specifically binds human galectin-7 (hGal-7), disrupts the formation of homodimers, and inhibits the pro-apoptotic activity of hGal-7 on Jurkat T cells.
Clinical significance of galectin-7 in vulvar squamous cell carcinoma.
New
Wu et al., Shenyang, China. In Oncol Lett, Dec 2015
UNASSIGNED: The present study reports the role of galectin-7 (Gal-7) expression in vulvar squamous cell carcinoma (VSCC) and its correlation with clinicopathological variables.
Identification of Differentially Expressed Proteins in the Serum of Colorectal Cancer Patients Using 2D-DIGE Proteomics Analysis.
New
Jamal et al., Kuala Lumpur, Malaysia. In Pathol Oncol Res, Nov 2015
Five proteins, namely apolipoprotein A1 (APOA1), apolipoprotein E (APOE), complement factor H (CFH), galectin-7 (GAL7) and synaptojanin-2 (SYNJ2) were validated using ELISA and only APOA1 and GAL-7 showed consistent findings.
Galectin-7 Regulates Keratinocyte Proliferation and Differentiation through JNK-miR-203-p63 Signaling.
New
Liu et al., Taipei, Taiwan. In J Invest Dermatol, Oct 2015
UNASSIGNED: Galectin-7, a member of the β-galactoside-binding protein family, is primarily expressed in stratified epithelial cells, including keratinocytes.
Regulatory Impact of Amniotic Membrane Transplantation on Presence of Adhesion/Growth-Regulatory Galectins-1 and -7 in Corneal Explants from Acanthamoeba Keratitis Patients: Clinical Note.
New
Gabius et al., Praha, Czech Republic. In Curr Eye Res, Oct 2015
The signal for galectin-7 was significantly decreased in the epithelium of AK patients and normalized after AMT.
Structural Basis Underlying the Binding Preference of Human Galectins-1, -3 and -7 for Galβ1-3/4GlcNAc.
Lin et al., Taipei, Taiwan. In Plos One, 2014
Galectins-1 and 3 were shown to have higher affinity for LN2 than for LN1, while galectin-7 displayed the reversed specificity.
Overexpression of galectin-7 in mouse epidermis leads to loss of cell junctions and defective skin repair.
Poirier et al., Paris, France. In Plos One, 2014
In human and mouse, galectin-7 is almost exclusively expressed in stratified epithelia, notably in the epidermis.
A Mutation in the Carbohydrate Recognition Domain Drives a Phenotypic Switch in the Role of Galectin-7 in Prostate Cancer.
St-Pierre et al., Québec, Canada. In Plos One, 2014
The observation that galectin-7 (gal-7) is specifically expressed in mammary myoepithelial (basal) cells prompted us to investigate whether this protein is expressed in the basal cells of other tissues.
Role of galectins in re-epithelialization of wounds.
Review
Panjwani, Boston, United States. In Ann Transl Med, 2014
Studies of the role of galectins in wound healing have revealed that galectin-3 promotes re-epithelialization of corneal, intestinal and skin wounds; galectin-7 promotes re-epithelialization of corneal, skin, kidney and uterine wounds; and galectins-2 and -4 promote re-epithelialization of intestinal wounds.
Galectin-7 as a marker of cholesteatoma residue and its detection during surgery by an immunofluorescent method--a preliminary study.
GeneRIF
Kameda et al., Japan. In Otol Neurotol, 2012
Because residual cholesteatoma matrix is considered to be one of the main causes of cholesteatoma recurrence, staining with galectin-7 at the time of operation would be a promising way to facilitate complete removal of the residue
EC-SOD induces apoptosis through COX-2 and galectin-7 in the epidermis.
GeneRIF
Kim et al., Seoul, South Korea. In J Dermatol Sci, 2012
Extracellular superoxide dismutase plays a role not only as a reactive oxygen species scavenger, but also as a pro-apoptotic factor via COX-2/galectin-7 pathways in the epidermis.
Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor.
GeneRIF
Acharya et al., Bath, United Kingdom. In Febs J, 2012
high resolution crystal structure of Gal-7 at 1.4 A (a dimer) and its 1.7 A structure in complex with an inhibitor, a sulfur-containing 2-O-benzylphosphate galactoside, a possible antineoplastic agent
A distinctive role for galectin-7 in cancer ?
Review
Grosset et al., Québec, Canada. In Front Biosci, 2011
In the case of galectin-7, several studies have reported alterations in its expression pattern during cancer progression.
Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells.
GeneRIF
Hughey et al., Pittsburgh, United States. In Am J Physiol Renal Physiol, 2011
Galectin-7 modulates the length of the primary cilia and wound repair in polarized kidney epithelial cells.
Significance of galectins-1, -3, -4 and -7 in the progression of squamous cell carcinoma of the tongue.
GeneRIF
Queiroz et al., Campina Grande, Brazil. In Pathol Res Pract, 2011
The intense immunoexpression of galectins-1, -3, and -7 suggests the participation of these proteins in oral carcinogenesis and their use as markers of biological behavior and tumor progression in squamous cell carcinoma of the tongue.
Galectin-7.
Review
Kiss et al., Mons, Belgium. In Cell Mol Life Sci, 2006
In addition, recent evidence indicates that galectin-7, designated as the product of the p53-induced gene 1 (PIG1), is a regulator of apoptosis through JNK activation and mitochondrial cytochrome c release.
90K (Mac-2 BP) and galectins in tumor progression and metastasis.
Review
Iacobelli et al., Chieti, Italy. In Glycoconj J, 2003
Mac-2 BP, also known as 90K, is a highly glycosylated, secreted protein extensively studied in human cancer, which binds galectin-1, galectin-3 and galectin-7.
Thermodynamic binding studies of galectin-1, -3 and -7.
Review
Brewer, United States. In Glycoconj J, 2003
Recent ITC studies have been performed with galectin-1, galectin-3 and galectin-7 and their interactions with sialylated and non-sialylated carbohydrates.
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