Enantioselective synthesis of vicinal (R,R)-diols by yeast butanediol dehydrogenase.
Montpellier, France. In Appl Environ Microbiol, Feb 2016
We have also developed a new variant of the "delitto perfetto" methodology to place BDH1 under the control of the GAL1 promoter, resulting in a yeast strain that overexpresses butanediol dehydrogenase and formate dehydrogenase activities in the presence of galactose and regenerates NADH in the presence of formate.
Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity.
Salzburg, Austria. In Pharmacol Rev, 2014
Galanin has been shown to regulate its numerous physiologic and pathophysiological processes through interactions with three G protein-coupled receptors, GAL1, GAL2, and GAL3, and signaling via multiple transduction pathways, including inhibition of cAMP/PKA (GAL1, GAL3) and stimulation of phospholipase C (GAL2).
Evolution of moonlighting proteins: insight from yeasts.
Madrid, Spain. In Biochem Soc Trans, 2014
It focuses on data available on hexokinase from Saccharomyces cerevisiae that moonlights in catabolite repression and on galactokinase from Kluyveromyces lactis that moonlights controlling the induction of the GAL genes.
Epigenetics of the yeast galactose genetic switch.
Mumbai, India. In J Biosci, 2009
The redundancy in signal transduction due to the presence of GAL1 (alternate signal transducer) also makes it a suitable model to understand the phenomenon of epigenetics.