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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Abhydrolase domain containing 16A

G-5, BAT5, G5 protein, BAT4
A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. The protein encoded by this gene is thought to be involved in some aspects of immunity. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010] (from NCBI)
Top mentioned proteins: HLA-G, MHC, G-3, HLA-B, BAT
Papers on G-5
Biochemical and pharmacological characterization of the human lymphocyte antigen B-associated transcript 5 (BAT5/ABHD16A).
Laitinen et al., Kuopio, Finland. In Plos One, 2013
BACKGROUND: Human lymphocyte antigen B-associated transcript 5 (BAT5, also known as ABHD16A) is a poorly characterized 63 kDa protein belonging to the α/β-hydrolase domain (ABHD) containing family of metabolic serine hydrolases.
Regulation and function of immunosuppressive molecule human leukocyte antigen G5 in human bone tissue.
Sensébé et al., Toulouse, France. In Faseb J, 2013
However, in mature osteoblasts, the expression of HLA-G5 protein was greatly suppressed whereas the proosteoclastogenic factor, RANKL, was concomitantly increased.
Soluble human leukocyte antigen-g5 activates extracellular signal-regulated protein kinase signaling and stimulates trophoblast invasion.
Lee et al., Beijing, China. In Plos One, 2012
Recombinant HLA-G5 protein over-expressed in E. coli BL21 was purified to near homogeneity.
[Expression of various subtypes of human leukocyte antigen-G in placenta of patients complicated with severe pre-eclampsia].
Chen et al., Beijing, China. In Zhonghua Fu Chan Ke Za Zhi, 2012
(2) HLA-G5 protein increased in the late-onset pre-eclampsia groups (1.8 ± 1.1 versus 1.1 ± 0.9, P < 0.05); the increase in the early-onset pre-eclampsia group is not obvious (1.6 ± 0.9 versus 1.4 ± 0.7, P > 0.05).
A systematic comparison of genome-scale clustering algorithms.
Langston et al., Bar Harbor, United States. In Bmc Bioinformatics, 2011
Clusters were grouped into small, medium, and large bins, and the Jaccard score of the top five scoring clusters in each bin were averaged and reported as the best average top 5 (BAT5) score for the particular method.
Variations in chromosomes 9 and 6p21.3 with risk of non-Hodgkin lymphoma.
Morton et al., Duarte, United States. In Cancer Epidemiol Biomarkers Prev, 2011
(RING1/RXRB; AIF1; BAT4).
Human lymphocyte antigen B-associated transcript 2, 3, and 5 polymorphisms and haplotypes are associated with susceptibility of Kawasaki disease and coronary artery aneurysm.
GeneRIF
Tsai et al., Taiwan. In J Clin Lab Anal, 2009
Results suggest BAT2 -8671, BAT3 8854, and BAT5 22655, 9569 SNPs as well as BAT haplotypes (ATTGTG and ATCATG) might be associated with higher Kawasaki disease susceptibility and coronary artery aneurysm formation.
Predicted poxvirus FEN1-like nuclease required for homologous recombination, double-strand break repair and full-size genome formation.
Moss et al., Bethesda, United States. In Proc Natl Acad Sci U S A, 2009
In this context, we investigated the function of the vaccinia virus G5 protein because it belongs to the FEN1-like family of nucleases and is conserved in all poxviruses.
The plastidic bile acid transporter 5 is required for the biosynthesis of methionine-derived glucosinolates in Arabidopsis thaliana.
Flügge et al., Köln, Germany. In Plant Cell, 2009
Here, we show that BAT5, which belongs to the putative bile acid transporter family, is the only member of this family that is transactivated by HAG1/MYB28, HAG2/MYB76, and HAG3/MYB29.
Missingness in the T1DGC MHC fine-mapping SNP data: association with HLA genotype and potential influence on genetic association studies.
Diabetes Genetics Consortium et al., Perth, Australia. In Diabetes Obes Metab, 2009
Comparisons of affected and unaffected siblings point to possible susceptibility regions additional to the classical HLA-DR3/4 alleles near BAT4-LY6G5B-BAT5 and NOTCH4.
Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis.
Brown et al., Australia. In Rheumatology (oxford), 2008
Quantitative RT-PCR was used to assess the expression of the positional candidate MHC class III genes APOM, BAT2, BAT3, BAT4, BAT5, AIF1, C6orf47, CSNK2beta and LY6G5C, and the housekeeper genes, hypoxanthine-guanine phosphoribosyltransferase (HPRT) and beta(2)-microglobulin (B2M) in 31 RA cases and 21 ethnically, age- and sex-matched healthy controls.
Soluble human leukocyte antigen-G5 in septic shock: marked and persisting elevation as a predictor of survival.
Carosella et al., Lyon, France. In Crit Care Med, 2007
CONCLUSIONS: The present results show a marked elevation of soluble human leukocyte antigen-G5 protein during septic shock.
An advanced sheep (Ovis aries, 2n = 54) cytogenetic map and assignment of 88 new autosomal loci by fluorescence in situ hybridization and R-banding.
Iannuzzi et al., Napoli, Italy. In Anim Genet, 2007
Eleven loci that were FISH-mapped in sheep (B3GAT2, ASCC3, RARSL, BRD2, POLR1C, PPP2R5D, TNRC5, BAT2, BAT4, CDC5L and OLA-DRA) are unassigned in cattle and goat.
Quantification and identification of soluble HLA-G isoforms.
Grosse-Wilde et al., Essen, Germany. In Tissue Antigens, 2007
Purified and well-defined HLA-G5 protein derived from insect SF9 cells transfected with HLA-G5 + human beta2m served as standard reagent.
A new cluster of genes within the human major histocompatibility complex.
Impact
Strominger et al., Cambridge, United States. In Science, 1989
The presence of the genes for BAT1 and BAT5 in the vicinity of HLA-B again raises the question of which gene in this region determines susceptibility to ankylosing spondylitis.
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