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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Fucosyltransferase 6

FUT6, Fuc-TVI, fucosyltransferase VI
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on FUT6
Functional analysis of α1,3/4-fucosyltransferase VI in human hepatocellular carcinoma cells.
GeneRIF
Wu et al., Shanghai, China. In Biochem Biophys Res Commun, 2012
these results suggest that FUT6 plays an important role in hepatocellular carcinoma growth by regulating the PI3K/Akt signaling pathway.
The biosynthesis of the selectin-ligand sialyl Lewis x in colorectal cancer tissues is regulated by fucosyltransferase VI and can be inhibited by an RNA interference-based approach.
GeneRIF
Dall'olio et al., Varese, Italy. In Int J Biochem Cell Biol, 2011
The biosynthesis of the selectin-ligand sialyl Lewis x in colorectal cancer tissues is regulated by fucosyltransferase VI and can be inhibited by an RNA interference-based approach.
Development of immunohistochemistry assays to assess GALNT14 and FUT3/6 in clinical trials of dulanermin and drozitumab.
GeneRIF
Ashkenazi et al., San Francisco, United States. In Clin Cancer Res, 2010
GALNT14 and FUT3/6 H-scores were significantly higher in non-small cell lung cancer cell lines sensitive to dulanermin and drozitumab versus resistant cell lines
Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells.
GeneRIF
Olofsson et al., Göteborg, Sweden. In Glycobiology, 2009
results suggested that PKR is the primary target for HSV-1 early RNA during induction of FUT3, FUT5, and FUT6
Transcriptional regulation of the fucosyltransferase VI gene in hepatocellular carcinoma cells.
GeneRIF
Matsumoto et al., Funabashi, Japan. In Glycoconj J, 2008
two defined regions in the 5'-flanking region of the FUT VI transcription start site are critical for FUT VI transcription in HepG2 cells
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