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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

N-acetyltransferase 6

FUS2, Putative tumor suppressor, Fus2p
This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring acetyl groups from acetyl CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located in the tumor suppressor gene region on chromosome 3p21.3 and the encoded protein may play a role in cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011] (from NCBI)
Top mentioned proteins: FUS, CAN, V1a, ACID, POLYMERASE
Papers on FUS2
Epigenetic Silencing of the Putative Tumor Suppressor Gene GLDC (Glycine Dehydrogenase) in Gastric Carcinoma.
New
Kim et al., Seoul, South Korea. In Anticancer Res, Jan 2016
CONCLUSION: GLDC is a putative tumor suppressor gene involved in gastric cancer progression and hypermethylation of the GLDC promoter regulates its transcriptional silencing.
An Amphiphysin-like Domain in Fus2p is Required for Rvs161p Interaction and Cortical Localization.
New
Rose et al., Princeton, United States. In G3 (bethesda), Jan 2016
Fus2p is a pheromone-induced protein that regulates cell wall removal during mating.
Loss of Leucine Zipper Putative Tumor Suppressor 1 (LZTS1) Expression Contributes to Lymph Node Metastasis of Breast Invasive Micropapillary Carcinoma.
New
Fu et al., Beijing, China. In Pathol Oncol Res, Sep 2015
Expression of leucine zipper putative tumor suppressor 1 (LZTS1) was frequently lost or reduced in breast cancer tissues.
Expression Analyses Revealed Thymic Stromal Co-Transporter/Slc46A2 Is in Stem Cell Populations and Is a Putative Tumor Suppressor.
New
Kim et al., Inch'ŏn, South Korea. In Mol Cells, Jun 2015
By combining conventional single cell analysis with flow cytometry and public database searches with bioinformatics tools, we extended the expression profiling of thymic stromal cotransporter (TSCOT), Slc46A2/Ly110, that was shown to be expressed in bipotent precursor and cortical thymic epithelial cells.
RASSF6; the Putative Tumor Suppressor of the RASSF Family.
Review
Hata et al., Tokyo, Japan. In Cancers (basel), 2014
Humans have 10 genes that belong to the Ras association (RA) domain family (RASSF).
Putative tumor suppressor gene SEL1L was downregulated by aberrantly upregulated hsa-mir-155 in human pancreatic ductal adenocarcinoma.
Frazier et al., Houston, United States. In Mol Carcinog, 2014
Sel-1-like (SEL1L) is a putative tumor suppressor gene that is significantly downregulated in human pancreatic ductal adenocarcinoma (PDA).
UCHL1 Is a Putative Tumor Suppressor in Ovarian Cancer Cells and Contributes to Cisplatin Resistance.
Lin et al., Hangzhou, China. In J Cancer, 2012
Ubiquitin carboxyl terminal hydrolase 1 (UCHL1) catalyzes the hydrolysis of COOH-terminal ubiquityl esters and amides.
A mechanism for the coordination of proliferation and differentiation by spatial regulation of Fus2p in budding yeast.
GeneRIF
Rose et al., Princeton, United States. In Genes Dev, 2012
potential premature activation of Fus2p in mitosis is prevented by cell cycle-dependent phosphorylation that overrides the mating pheromone-induced phosphorylation that drives nuclear export.
Cdc42p and Fus2p act together late in yeast cell fusion.
GeneRIF
Rose et al., Princeton, United States. In Mol Biol Cell, 2012
Cdc42p acts at a late stage in cell fusion in concert with a key cell fusion regulator, Fus2p, which contains a Dbl-homology domain. We find that Fus2p binds specifically with activated Cdc42p, and binding is blocked by the cdc42-138 mutation.
Reduced Expression of RNA Binding Protein CELF2, a Putative Tumor Suppressor Gene in Colon Cancer.
Anant et al., United States. In Immunogastroenterology, 2011
BACKGROUND & AIMS: Colon cancer is the third leading cause of cancer death in both men and women in the United States.
Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene Friend leukemia virus integration 1 gene.
Ge et al., Shanghai, China. In Cancer, 2011
BACKGROUND: Tumor suppressor microRNA miR-145 is commonly down-regulated in colon carcinoma tissues, but its specific role in tumors remains unknown.
The class V myosin Myo2p is required for Fus2p transport and actin polarization during the yeast mating response.
GeneRIF
Rose et al., Princeton, United States. In Mol Biol Cell, 2009
Fus2p and Sec4p, another Myo2p cargo associated with exocytotic vesicles, reside predominantly on different cellular organelles.
Antagonistic regulation of Fus2p nuclear localization by pheromone signaling and the cell cycle.
GeneRIF
Rose et al., Princeton, United States. In J Cell Biol, 2009
Results indicate a novel mechanism by which pheromone-induced proteins, including Fus2, are regulated during the transition from mitosis to conjugation.
Dynamic localization of yeast Fus2p to an expanding ring at the cell fusion junction during mating.
GeneRIF
Rose et al., Princeton, United States. In J Cell Biol, 2008
Fus2p dots are transported along actin cables, possibly in association with vesicles.
[SNP767A/T of FUS2 gene and lung cancer risk in Chinese population].
He et al., Beijing, China. In Zhongguo Fei Ai Za Zhi, 2006
BACKGROUND: FUS2 gene locating at 3p21.3 is considered a promising candidate tumor suppressor gene.
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