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FtsJ homolog 2

FTSJ2
The protein encoded by this gene is a member of the S-adenosylmethionine-binding protein family. It is a nucleolar protein and it may be involved in the processing and modification of rRNA. This gene has been suggested to be involved in cell cycle control and DNA repair. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, ACID, CL1, SPB-1, PRT1
Papers on FTSJ2
MRM2 and MRM3 are involved in biogenesis of the large subunit of the mitochondrial ribosome.
Minczuk et al., Cambridge, United Kingdom. In Mol Biol Cell, 2014
Here we investigate two methyltransferases, MRM2 (also known as RRMJ2, encoded by FTSJ2) and MRM3 (also known as RMTL1, encoded by RNMTL1), that are responsible for modification of nucleotides of the 16S rRNA A-loop, an essential component of the peptidyl transferase center.
FTSJ2, a heat shock-inducible mitochondrial protein, suppresses cell invasion and migration.
Chen et al., T'ai-chung-shih, Taiwan. In Plos One, 2013
In mammals, three close homologs of RrmJ have been identified and have been designated as FTSJ1, FTSJ2 and FTSJ3; however, little is known about these genes.
Delineation of a less than 200 kb minimal deleted region for cardiac malformations on chromosome 7p22.
Scott et al., Houston, United States. In Am J Med Genet A, 2011
This minimal deleted region spans all, or portions, of the coding regions of four known genes-MAD1L1, FTSJ2, NUDT1, and SNX8-and may include upstream regulatory elements of EIF3B.
Integrative genomic and gene expression analysis of chromosome 7 identified novel oncogene loci in non-small cell lung cancer.
Lam et al., Vancouver, Canada. In Genome, 2008
In this study, we demonstrated that multiple loci on chromosome 7 are indeed amplified in NSCLC, and through integrative analysis of gene dosage alterations and parallel gene expression changes, we identified new lung cancer oncogene candidates, including FTSJ2, NUDT1, TAF6, and POLR2J.
Identification and characterization of FTSJ2, a novel human nucleolar protein homologous to bacterial ribosomal RNA methyltransferase.
GeneRIF
Jin et al., Hong Kong, Hong Kong. In Genomics, 2002
FTSJ2 is a nucleolar RNA methyltransferase involved in eukaryotic RNA processing and modification.
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