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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Fructose-1,6-bisphosphatase 1

Fructose-Bisphosphatase, fructose-1,6-bisphosphatase, FBPase, S100A12, P-6
Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, HAD, ACID, Insulin, S-100
Papers using Fructose-Bisphosphatase antibodies
PTP1B as a drug target: recent developments in PTP1B inhibitor discovery
Tiganis Tony et al., In Diabetes, 2006
... Expression of human fructose-1,6-bisphosphatase in the liver of transgenic mice results in increased ...
Pseudomonas aeruginosa cystic fibrosis isolates induce rapid, type III secretion-dependent, but ExoU-independent, oncosis of macrophages and polymorphonuclear neutrophils.
Hofmann Andreas, In PLoS ONE, 1999
... Co., St Louis, MO, USA); S100A8 (Calgranulin A, C-19) goat polyclonal antibody, donkey-anti-goat IgG antibody, S100A12 (Calgranulin C, 19F5) monoclonal antibody (Santa Cruz Biotechnology, Inc., Santa Cruz, CA, ...
Papers on Fructose-Bisphosphatase
Calprotectin (S100A8/A9) and S100A12 are associated with measures of disease activity in a longitudinal study of patients with rheumatoid arthritis treated with infliximab.
Halse et al., Bergen, Norway. In Scand J Rheumatol, Feb 2016
OBJECTIVES: The pro-inflammatory proteins calprotectin (a heterocomplex of S100A8/A9) and S100A12 have been associated with disease activity in rheumatoid arthritis (RA).
Validation of an enzyme-linked immunosorbent assay (ELISA) for the measurement of canine S100A12.
Steiner et al., College Station, United States. In Vet Clin Pathol, Feb 2016
BACKGROUND: Canine S100 calcium-binding protein A12 (cS100A12) shows promise as biomarker of inflammation in dogs.
Elevated levels of S100A12 in the seminal plasma of infertile men with varicocele.
Khorramdelazad et al., Rafsanjān, Iran. In Int Urol Nephrol, Feb 2016
S100A12 is a member of the S100 family of calcium-binding proteins with principal extracellular activities.
Seasonal proteome changes of nasal mucus reflect perennial inflammatory response and reduced defence mechanisms and plasticity in allergic rhinitis.
Lang-Loidolt et al., Graz, Austria. In J Proteomics, Jan 2016
GSTP1 (0.5-fold), ELANE (0.4-fold), HIST1H2BK (0.3-fold), S100A8 (0.2-fold), S100A12 (0.2-fold) and ARHGDIB (0.1-fold) were significantly less abundant in season.
S100A12 and the S100/Calgranulins: Emerging Biomarkers for Atherosclerosis and Possibly Therapeutic Targets.
Hofmann Bowman et al., Chicago, United States. In Arterioscler Thromb Vasc Biol, Dec 2015
This review focuses on S100/calgranulin proteins (S100A8, S100A9, and S100A12) and their receptor RAGE in mediating vascular inflammation.
Serum Cytokines as Biomarkers in Islet Cell Transplantation for Type 1 Diabetes.
Roep et al., Leiden, Netherlands. In Plos One, Dec 2015
Patterns of cytokines could distinguish good graft function from insufficient function including IFN-α, LIF, SCF and IL-1RII before and after transplantation, by IL-16, CCL3, BDNF and M-CSF only before and by IL-22, IL-33, KIM-1, S100A12 and sCD14 after transplantation.
Fructose-1,6-bisphosphatase opposes renal carcinoma progression.
Simon et al., Philadelphia, United States. In Nature, 2014
Here we used an integrative approach comprising pan-metabolomic profiling and metabolic gene set analysis and determined that the gluconeogenic enzyme fructose-1,6-bisphosphatase 1 (FBP1) is uniformly depleted in over six hundred ccRCC tumours examined.
Fecal biomarkers in the diagnosis and monitoring of Crohn's disease.
Kamm et al., Melbourne, Australia. In Inflamm Bowel Dis, 2014
Fecal biomarkers such as calprotectin, lactoferrin, and S100A12 are predominantly derived from neutrophils, are easily detectable in the feces, and are emerging as valuable markers of intestinal inflammation.
[Fecal lactoferrin in identifying and management of inflammatory bowel disease].
Mroczkowska-Juchkiewicz et al., In Pol Merkur Lekarski, 2014
Recently, there has been increasing interest in identifying biomarkers, i.e. calprotectin, lactoferrin, mieloperoxidasis or S100A12 protein in faeces.
Exocytosis and Endocytosis of Small Vesicles across the Plasma Membrane in Saccharomyces cerevisiae.
Chiang et al., State College, United States. In Membranes (basel), 2013
When Saccharomyces cerevisiae is starved of glucose, the gluconeogenic enzymes fructose-1,6-bisphosphatase (FBPase), phosphoenolpyruvate carboxykinase, isocitrate lyase, and malate dehydrogenase, as well as the non-gluconeogenic enzymes glyceraldehyde-3-phosphate dehydrogenase and cyclophilin A, are secreted into the periplasm.
Systematic identification of allosteric protein-metabolite interactions that control enzyme activity in vivo.
Sauer et al., Zürich, Switzerland. In Nat Biotechnol, 2013
We identified allosteric interactions that govern the reversible switch between gluconeogenesis and glycolysis, including one by which pyruvate activates fructose-1,6-bisphosphatase.
Biomarkers in Exhaled Breath Condensate and Serum of Chronic Obstructive Pulmonary Disease and Non-Small-Cell Lung Cancer.
Thomas et al., Sydney, Australia. In Int J Chronic Dis, 2012
In the serum, S100A8, S100A9, and S100A12 of the S100 proteins are proinflammatory markers.
Gut-derived serotonin is a multifunctional determinant to fasting adaptation.
Karsenty et al., New York City, United States. In Cell Metab, 2012
In hepatocytes, GDS signaling through Htr2b promotes gluconeogenesis by enhancing activity of two rate-limiting gluconeogenic enzymes, FBPase and G6Pase.
S100A12 expression in thoracic aortic aneurysm is associated with increased risk of dissection and perioperative complications.
Hofmann Bowman et al., Chicago, United States. In J Am Coll Cardiol, 2012
Data indicate that S100A12 is up-regulated in Thoracic Aortic Aneurysm Dissection (TAAD) and may contribute to the pathogenesis of TAAD by initiating apoptosis of SMC, at least in part via increased oxidative stress.
Protein disulfide isomerase-associated 6 is an ATF6-inducible ER stress response protein that protects cardiac myocytes from ischemia/reperfusion-mediated cell death.
Glembotski et al., San Diego, United States. In J Mol Cell Cardiol, 2012
By facilitating disulfide bond formation, and enhanced ER protein folding, PDIA6 may contribute to the protective effects of ATF6 in the ischemic mouse heart.
Role of S100A12 in the pathogenesis of osteoarthritis.
Ishiguro et al., Nagoya, Japan. In Biochem Biophys Res Commun, 2012
these data indicate the possible involvement of S100A12 in the development of osteoarthritis by up-regulating MMP-13 and VEGF via p38 MAPK and NF-kappaB pathways.
The role of liver fructose-1,6-bisphosphatase in regulating appetite and adiposity.
Fam et al., Melbourne, Australia. In Diabetes, 2012
This is the first study to identify liver FBPase as a previously unknown regulator of appetite and adiposity and describes a novel process by which the liver participates in body weight regulation.
miR-27b targets KSRP to coordinate TLR4-mediated epithelial defense against Cryptosporidium parvum infection.
Chen et al., Omaha, United States. In Plos Pathog, 2011
data suggest that miR-27b targets KSRP and modulates iNOS mRNA stability following C. parvum infection, a process that may be relevant to the regulation of epithelial anti-microbial defense in general
S100A12 (EN-RAGE) in monitoring Kawasaki disease.
Roth et al., Münster, Germany. In Lancet, 2003
S100A12 is highly expressed and shows a close correlation with disease activity in a systemic human vasculitis (Kawasaki disease).
Regulated import and degradation of a cytosolic protein in the yeast vacuole.
Schekman et al., Berkeley, United States. In Nature, 1991
The key regulatory enzyme in gluconeogenesis, fructose 1,6-bisphosphatase (FBPase) is subject to glucose-stimulated proteolytic degradation in Saccharomyces cerevisiae.
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