Cryptic 13q34 and 4q35.2 Deletions in an Italian Family.
Parma, Italy. In Cytogenet Genome Res, Jan 2016
The terminal deletion in 4q35.2 contains other OMIM genes (FRG1, FRG2 and DBET); moreover, the 4q region is reported as a susceptibility locus for Crohn's disease, diagnosed in the proband's father.
Super-telomeres in transformed human fibroblasts.
Pavia, Italy. In Biochim Biophys Acta, 2013
Super-telomeres neither influenced subtelomeric region global methylation nor the expression of the subtelomeric gene FRG1, attesting the lack of a clear-cut relationship between telomere length, subtelomeric DNA methylation and expression in human cells.