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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Dec 2016.

Nuclear fragile X mental retardation protein interacting protein 2

Fragile X Mental Retardation Protein
Top mentioned proteins: FMR1, CAN, mGluR, OUT, V1a
Papers on Fragile X Mental Retardation Protein
Molecular medicine of fragile X syndrome: based on known molecular mechanisms.
Review
New
Duan et al., Changsha, China. In World J Pediatr, Feb 2016
RESULTS: The pathological mechanisms of FXS were categorized on the basis of neuroanatomy, synaptic structure, synaptic transmission and fragile X mental retardation protein (FMRP) loss of function.
Disrupted Cortical State Regulation in a Rat Model of Fragile X Syndrome.
New
Colonnese et al., Washington, D.C., United States. In Cereb Cortex, Feb 2016
To begin to identify the neural causes of these deficits, we examined juvenile rats lacking the Fragile X mental retardation protein (FMR-KO) for disruption of cortical activity related to attention and arousal.
Fragile X Mental Retardation Protein expression in the retina is regulated by light.
New
Calaza et al., Rio de Janeiro, Brazil. In Exp Eye Res, Jan 2016
UNASSIGNED: Fragile X Mental Retardation Protein (FMRP) is a RNA-binding protein that modulates protein synthesis at the synapse and its function is regulated by glutamate.
JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse.
New
Geschwind et al., Los Angeles, United States. In Neuron, Jan 2016
Here, we provide multiple lines of evidence that JAKMIP1 is a component of polyribosomes and an RNP translational regulatory complex that includes fragile X mental retardation protein, DEAD box helicase 5, and the poly(A) binding protein cytoplasmic 1.
Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish.
New
Appelbaum et al., Ramat Gan, Israel. In Plos Genet, Dec 2015
The cause for this X-linked disorder is the silencing of the fragile X mental retardation 1 (fmr1) gene and the absence of the fragile X mental retardation protein (Fmrp).
Human pluripotent stem cell models of Fragile X syndrome.
Review
New
Zhao et al., Madison, United States. In Mol Cell Neurosci, Dec 2015
The causal mutation in FXS is a trinucleotide CGG repeat expansion in the FMR1 gene that leads to human specific epigenetic silencing and loss of Fragile X Mental Retardation Protein (FMRP) expression.
Cell-Type Specific Channelopathies in the Prefrontal Cortex of the fmr1-/y Mouse Model of Fragile X Syndrome(1,2,3).
New
Brager et al., Austin, United States. In Eneuro, Nov 2015
Fragile X syndrome (FXS) is caused by transcriptional silencing of the fmr1 gene resulting in the loss of fragile X mental retardation protein (FMRP) expression.
Dysregulation and restoration of translational homeostasis in fragile X syndrome.
Review
New
Impact
Klann et al., Worcester, United States. In Nat Rev Neurosci, Oct 2015
Fragile X syndrome (FXS), the most-frequently inherited form of intellectual disability and the most-prevalent single-gene cause of autism, results from a lack of fragile X mental retardation protein (FMRP), an RNA-binding protein that acts, in most cases, to repress translation.
Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back.
Review
New
Berry-Kravis et al., Cincinnati, United States. In Neurotherapeutics, Jul 2015
Fragile X syndrome (FXS), an inherited intellectual disability often associated with autism, is caused by the loss of expression of the fragile X mental retardation protein.
[General and Specific Mechanisms of Visual Cognitive Function Impairment in People with FMRP Deficit].
Review
New
Gorbachevskaya et al., In Zh Vyssh Nerv Deiat Im I P Pavlova, May 2015
The syndrome is associated with deficit of fragile X mental retardation protein following FMR1-gene mutation.
microRNAs and Fragile X Syndrome.
Lin, Santa Fe Springs, United States. In Adv Exp Med Biol, 2014
The etiology of FXS is linked to the expansion of the CGG trinucleotide repeats, r(CGG), suppressing the fragile X mental retardation 1 (FMR1) gene on the X chromosome, resulting in a loss of fragile X mental retardation protein (FMRP) expression, which is required for regulating normal neuronal connectivity and plasticity.
SnapShot: FMRP interacting proteins.
Impact
Bagni et al., Leuven, Belgium. In Cell, 2014
The Fragile X syndrome, caused by the absence or mutation of fragile X mental retardation protein, FMRP, is a the common component of inherited intellectual disability and autism.
SnapShot: FMRP mRNA targets and diseases.
Impact
Bagni et al., Leuven, Belgium. In Cell, 2014
FMRP, or fragile X mental retardation protein is an RNA-binding protein.
A chromatin-dependent role of the fragile X mental retardation protein FMRP in the DNA damage response.
Impact
Shi et al., Boston, United States. In Cell, 2014
Fragile X syndrome, a common form of inherited intellectual disability, is caused by loss of the fragile X mental retardation protein FMRP.
A polygenic burden of rare disruptive mutations in schizophrenia.
Impact
Sklar et al., Cambridge, United States. In Nature, 2014
Similar to reports in autism, targets of the fragile X mental retardation protein (FMRP, product of FMR1) are enriched for case mutations.
82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization.
GeneRIF
Mandel et al., Illkirch-Graffenstaden, France. In Hum Mol Genet, 2003
identification and characterization of FIP-82, a novel FMRP-interacting protein associated to polyribosomes as a component of mRNP complexes containing FMRP
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