Cellular functions of programmed cell death 5.
Beijing, China. In Biochim Biophys Acta, Feb 2016
Recent evidence suggests that PDCD5 participates in immune regulation by promoting regulatory T cell function via the PDCD5-TIP60-FOXP3 pathway.
Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases.
More papers using
Syracuse, United States. In Nat Rev Rheumatol, Jan 2016
Both mTORC1 and mTORC2 inhibit the development of CD4(+)CD25(+)FoxP3(+) T regulatory (TREG) cells and, indirectly, mTORC2 favours the expansion of T follicular helper (TFH) cells which, similarly to DN T cells, promote B-cell activation and autoantibody production.
IFN-g production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo
In PLoS ONE, 2004
... anti-CD86 (BU63, Serotec), anti-CD123 (9F5, BD Biosciences), anti-CD127 (HIL-7R-M21, BD Pharmingen), anti-CD303 (AC144, Miltenyi Biotec), anti-Foxp3 (259D, eBioscience), anti-CTLA-4 (BNI3, BD Biosciences) ...