[Epidermal aging and anti-aging strategies].
Halle, Germany. In Hautarzt, Jan 2016
Signs of cellular senescence are reduced proliferation of keratinocytes, cumulation of dysplastic keratinocytes, various mutations (e.g., c-Fos/c-Jun, STAT3, FoxO1), as well as multiple lipid or amino acid metabolic aberrations (e.g., production of advanced glycation endproducts).
Physiological role of aquaporin 5 in salivary glands.
Tokushima, Japan. In Pflugers Arch, Dec 2015
Elevated NF-κB and AP-1 (c-Fos/c-Jun) form a complex that can bind to the NF-κB-responsive element on the AQP5 promoter and thus potentially downregulate AQP5 transcription.
Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth.
Padova, Italy. In Nat Cell Biol, Sep 2015
By ChIP-seq analyses in breast cancer cells, we discovered that the YAP/TAZ transcriptional response is pervasively mediated by a dual element: TEAD factors, through which YAP/TAZ bind to DNA, co-occupying chromatin with activator protein-1 (AP-1, dimer of JUN and FOS proteins) at composite cis-regulatory elements harbouring both TEAD and AP-1 motifs.
A temporal shift in the circuits mediating retrieval of fear memory.
San Juan, Puerto Rico. In Nature, Apr 2015
Consistent with this, the paraventricular nucleus of the thalamus (PVT), a subregion of the dorsal midline thalamus, showed increased c-Fos expression only at late time points, indicating that the PVT is gradually recruited for fear retrieval.
Function through synthesis-informed design.
Stanford, United States. In Acc Chem Res, Apr 2015
In this Account, we address studies in our laboratory on function-oriented synthesis (FOS), a strategy to achieve function by design and with synthetic economy.
Neurologic Regulation and Orthodontic Tooth Movement.
More papers using
In Front Oral Biol, 2014
Tooth movement activates peripheral sensory nerve endings, which transmit painful signals to the brain after being processed at the trigeminal spinal nucleus, resulting in local expression of pain related genes, such as c-Fos.