GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 19 Aug 2016.
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008] (from
Adeyemi et al., Lagos, Nigeria. In Drug Res (stuttg), Feb 2016
Methods: Male albino mice were pretreated with monoaminergic or cholinergic receptor antagonists, L-arginine or N(G)-nitro-L-arginine (nitric oxide synthase inhibitor) (at doses reported to block the in vivo effect of the agonists), 15 min before oral administration of CF (100 mg/kg), 1 h later, the forced swim test (FST) in mice was carried out.
Li et al., Zhengzhou, China. In Neurosci Lett, Feb 2016
The present results showed that exogenous corticosterone injection caused depressive-like behaviors in mice, such as decreased sucrose intake in sucrose preference test (SPT) and increased immobility time in forced swimming test (FST).
Arora et al., Minneapolis, United States. In Transl Res, Jan 2016
In this review, we summarize the data relevant to angiogenic factors that may contribute to healing after aGVHD (epidermal growth factor and vascular endothelial growth factor A) and angiogenic factors that may promote inflammation after aGVHD (placental growth factor and follistatin).
Wieronska et al., Kraków, Poland. In Curr Neuropharmacol, Jun 2015
Social interaction,modified forced swim test (FST)and novel object recognition (NOR) test were used as the models for negative and cognitive symptoms of schizophrenia.LSP4-2022 dose-dependently (0.5-2 mg/kg) inhibited hyperactivity induced by MK-801 or amphetamine, and DOI-induced head twitches.
Sampath et al., Singapore, Singapore. In Nature, 2013
Expression of primate-specific exonic microRNA-198 (miR-198), located in the 3'-untranslated region of follistatin-like 1 (FSTL1) messenger RNA, switches to expression of the linked open reading frame of FSTL1 upon wounding in a human ex vivo organ culture system.
Gregorevic et al., Australia. In J Cell Biol, 2012
regulation of Smad3- and mTOR-dependent events by follistatin occurred independently of overexpression or knockout of myostatin, a key repressor of muscle development that can regulate Smad3 and mTOR signaling and that is itself inhibited by follistatin
Schroeder et al., Los Angeles, United States. In J Strength Cond Res, 2012
After eccentric exercise, postmenopausal women not using hormone therapy (HT) expressed higher levels of follistatin while postmenopausal women using HT showed a significant increased expression over controls.
Tricoli et al., São Paulo, Brazil. In Med Sci Sports Exerc, 2012
LIR was able to induce gains in 1RM and quadriceps CSA similar to those observed after traditional HI. These responses may be related to the concomitant decrease in MSTN and increase in FLST isoforms, GASP-1, and SMAD-7 mRNA gene expression.
Administration of an interfering peptide that disrupts the D1-D2 receptor complex substantially reduced immobility in the forced swim test (FST) without affecting locomotor activity, and decreased escape failures in learned helplessness tests in rats.