Erythropoiesis in vertebrates: from ontogeny to clinical relevance.
São Paulo, Brazil. In Front Biosci (elite Ed), Dec 2015
Several transcription factors and cytokines, such as GATA-1, GATA-2, FOG-1 and erythropoietin (EPO), constitute an elaborated molecular network that regulates erythropoiesis as they are involved in the differentiation and maturation of RBCs.
Fibromyalgia: the prototypical central sensitivity syndrome.
Brentwood, United States. In Curr Rheumatol Rev, 2014
The core FM symptom domains can be recalled using the FIBRO mnemonic and include Fatigue and Fog (cognitive dysfunction), Insomnia (difficulties with all aspects of sleep including initiation, maintenance and restorative), Blues (depression and anxiety), Rigidity (stiffness in muscles and joints) and Ow! (widespread pain and tenderness).
Inherited thrombocytopenia due to GATA-1 mutations.
Indianapolis, United States. In Semin Thromb Hemost, 2011
A wide variety of mutations in GATA-1 affect its function, as well as its interaction with its cofactors (especially Friend of GATA) and the genes upon which GATA-1 acts.
Mechanotransduction in development.
Paris, France. In Curr Top Dev Biol, 2010
We discuss the known underlying molecular mechanisms involved in such mechanotransduction processes, including the Armadillo/β-catenin activation of Twist and the Fog-dependent stabilization of Myosin-II.