Enzymatic repair of Amadori products.
Brussels, Belgium. In Amino Acids, 2012
Mammals and birds also have an enzyme designated 'FN3K-related protein' (FN3KRP), which shares ≈ 65% sequence identity with FN3K.
Plant ribulosamine/erythrulosamine 3-kinase, a putative protein-repair enzyme.
Brussels, Belgium. In Biochem J, 2005
The homologous mammalian enzyme, FN3K-RP (FN3K-related protein), does not phosphorylate fructosamines but ribulosamines, which are probably formed through a spontaneous reaction of amines with ribose 5-phosphate, an intermediate of the pentose-phosphate pathway and the Calvin cycle.
Enzymatic deglycation--a new paradigm or an epiphenomenon?
United States. In Biochem Soc Trans, 2003
Following the discovery of FN3K (fructosamine 3-kinase), and more recently of FN3KRP (FN3K-related protein), research in our laboratory has been focused on testing the enzymatic deglycation hypothesis and investigating the roles of FN3K and FN3KRP.