Gastrointestinal stromal tumors: chemotherapy and
In Rare Tumors, 2001
... (PDGFR-β, 1:100, Calbiochem, Schwalbach/Ts, Germany), and stem cell tyrosine kinase 1 (FLT3, 1:100, Abcam, Cambridge, UK), as ...
INFERENCE OF PERSONALIZED DRUG TARGETS VIA NETWORK PROPAGATION.
Tel Aviv-Yafo, Israel. In Pac Symp Biocomput, Dec 2015
Finally, we focus on the largest AML patient subgroup (~30%) which is characterized by an FLT3 mutation, and utilize our prediction score to rank patient sensitivity to inhibition of each predicted target, reproducing previous findings of in-vitro experiments.