Papers using
FKBP51
antibodies
A polycomb repression signature in metastatic prostate cancer predicts cancer outcome.Randau Lennart, In PLoS ONE, 2006
... Santa Cruz, CA.), FASN (fatty acid synthase, mouse monoclonal, BD Transduction Labs, Franklin Lakes, NJ), FKBP5 (FK506 binding protein 5, mouse monoclonal, BD Transduction Labs), AR (mouse monoclonal-AR441, Lab Vision, Fremont, CA), GARS (glycyl-tRNA synthetase, rabbit polyclonal, Abcam, Cambridge, MA), WARS (tryptophanyl-tRNA ...
Papers on
FKBP51
Glucocorticoid receptors, brain-derived neurotrophic factor, serotonin and dopamine neurotransmission are associated with interferon-induced depression.Martín-Santos et al., Barcelona, Spain. In Int J Neuropsychopharmacol, Jan 2016
We genotyped several functional polymorphisms of interleukin-28 (IL28B), indoleamine 2,3-dioxygenase (IDO-1), serotonin receptor-1A (HTR1A), catechol-O-methyl transferase (COMT), glucocorticoid receptors (GCR1 and GCR2), brain-derived neurotrophic factor (BDNF) and FK506 binding protein 5 (FKBP5) genes.
What can HPA axis-linked genes tell us about anxiety disorders in adolescents?Manfro et al., Porto Alegre, Brazil. In Trends Psychiatry Psychother, Dec 2015
We extracted DNA from saliva and genotyped polymorphisms in HPA-linked genes (FKBP5: rs3800373, rs9296158, rs1360780, rs9470080 and rs4713916; NR3C1: rs6198; CRHR1: rs878886; and SERPINA6: rs746530) with real time polymerase chain reaction (PCR).
Stress-induced mechanisms in mental illness: A role for glucocorticoid signalling.Riva et al., London, United Kingdom. In J Steroid Biochem Mol Biol, Sep 2015
Indeed, exposure to chronic stress early in life as well as in adulthood has been shown to reduce the expression of glucocorticoid receptors (GR), also through epigenetic mechanisms, and to up-regulate the expression of the co-chaperone gene FKBP5, which restrains GR activity by limiting the translocation of the receptor complex to the nucleus.
Steroid Receptor-Associated Immunophilins: A Gateway to Steroid Signalling.Ward et al., Australia. In Clin Biochem Rev, May 2015
The steroid receptor-associated immunophilins FKBP51, FKBP52, CyP40 and PP5 have specific roles in steroid receptor function that impact steroid hormone-binding affinity, nucleocytoplasmic shuttling and transcriptional activation of target genes in a tissue-specific manner.
Neuropsin cleaves EphB2 in the amygdala to control anxiety.Pawlak et al., Leicester, United Kingdom. In Nature, 2011
Here we show in mice that the serine protease neuropsin is critical for stress-related plasticity in the amygdala by regulating the dynamics of the EphB2-NMDA-receptor interaction, the expression of Fkbp5 and anxiety-like behaviour.