Papers on
FISP
Interleukin-4 and interferon-γ orchestrate an epithelial polarization in the airways.Schmidt-Weber et al., München, Germany. In Mucosal Immunol, Dec 2015
Furthermore, the IL-4-dependent induction of IL-24 observed in rhinitis patients was downregulated by IFN-γ, and therefore IL-24 represents a potential biomarker of allergic inflammation and a Th2 polarized condition of the epithelium.Mucosal Immunology advance online publication, 18 November 2015; doi:10.1038/mi.2015.110.
Differential expression of inflammation-related genes in IL-4 transgenic mice before and after the onset of atopic dermatitis skin lesions.Chan et al., Chicago, United States. In Mol Cell Probes, Dec 2015
Particularly, CXCL5, IL-1β, IL-24, IL-6, oncostatin M, PTGS2, FPR1 and REG3γ are up-regulated several hundred-fold.
Fibrosis Related Inflammatory Mediators: Role of the IL-10 Cytokine Family.Vannay et al., Budapest, Hungary. In Mediators Inflamm, 2014
In the present review we provide an overview of the common key mediators of organ fibrosis highlighting the role of interleukin-10 (IL-10) cytokine family members (IL-10, IL-19, IL-20, IL-22, IL-24, and IL-26), which recently came into focus as tissue remodeling-related inflammatory cytokines.
IL-10 function, regulation, and in bacterial keratitis.McClellan et al., Detroit, United States. In J Ocul Pharmacol Ther, 2014
The interleukin (IL)-10 family of cytokines, composed of 9 members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, and 3 distantly related members, IL-28A, IL-28B, and IL-29, plays a central role in this regulation.
MDA-7/IL-24: multifunctional cancer killing cytokine.Fisher et al., Richmond, United States. In Adv Exp Med Biol, 2013
First identified almost two decades ago as a novel gene differentially expressed in human melanoma cells induced to terminally differentiate, MDA-7/IL-24 has since shown great potential as an anti-cancer gene.
Chapter One---Cancer terminator viruses and approaches for enhancing therapeutic outcomes.Fisher et al., Richmond, United States. In Adv Cancer Res, 2011
Based on these considerations, a novel class of cancer destroying adenoviruses have been produced, cancer terminator viruses (CTVs), in which cancer-specific replication is controlled by the progression-elevated gene-3 promoter and replicating viruses produce a second transgene encoding an apoptosis-inducing and immunomodulatory cytokine, either melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24) or interferon-γ.
Regulation and functions of the IL-10 family of cytokines in inflammation and disease.Hymowitz et al., San Francisco, United States. In Annu Rev Immunol, 2010
The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, and the more distantly related IL-28A, IL-28B, and IL-29.