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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Fission 1

Fis1, hFis1, Fis1p
The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission (James et al., 2003 [PubMed 12783892]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: Utrophin, Dynamin I, CAN, Mdv1, V1a
Papers using Fis1 antibodies
Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death
McBride Heidi M. et al., In The Journal of Cell Biology, 2003
... (BD Biosciences), mouse IgG (Sigma-Aldrich), α-hFis1 (Biovision), and α-Tom20 rabbit serum ...
Papers on Fis1
Insulin resistance by TNF-α is associated with mitochondrial dysfunction in 3T3-L1 adipocytes and is ameliorated by punicic acid, a PPARγ agonist.
Raghu et al., Thiruvananthapuram, India. In Mol Cell Endocrinol, Oct 2015
In addition, treatment with PA was found to ameliorate TNF-α induced alterations in proteins associated with mitochondrial dynamics like FIS1 and OPA1.
Mitochondrial fission protein MoFis1 mediates conidiation and is required for full virulence of the rice blast fungus Magnaporthe oryzae.
Lu et al., Hangzhou, China. In Microbiol Res, Sep 2015
The mitochondrial fission protein Fis1 regulates yeast mitochondrial fission and is required for ethanol-induced mitochondrial fragmentation and apoptosis.
miR-483-5p determines mitochondrial fission and cisplatin sensitivity in tongue squamous cell carcinoma by targeting FIS1.
Li et al., Guangzhou, China. In Cancer Lett, Aug 2015
In this study, we show that the mitochondrial fission protein FIS1 is upregulated upon cisplatin treatment in tongue squamous cell carcinoma (TSCC) cells.
Asymmetric damage segregation at cell division via protein aggregate fusion and attachment to organelles.
Tolić et al., Cambridge, United States. In Bioessays, Jul 2015
Later, aggregates move to the mitochondrial surface through fis1-dependent association.
SET overexpression in HEK293 cells regulates mitochondrial uncoupling proteins levels within a mitochondrial fission/reduced autophagic flux scenario.
Leopoldino et al., Ribeirão Preto, Brazil. In Biochem Biophys Res Commun, Apr 2015
SET overexpression also (i) decreased the area of mitochondria and increased the number of organelles and lysosomes, (ii) increased mitochondrial fission, as demonstrated by increased FIS1 mRNA and FIS-1 protein levels, an apparent accumulation of DRP-1 protein, and an increase in the VDAC protein level, and (iii) reduced autophagic flux, as demonstrated by a decrease in LC3B lipidation (LC3B-II) in the presence of chloroquine.
Phosphorylation of Pex11p does not regulate peroxisomal fission in the yeast Hansenula polymorpha.
Williams et al., Groningen, Netherlands. In Sci Rep, 2014
However, phosphorylation of PpPex11p was proposed to influence its interaction with Fis1p, another component of the organellar fission machinery.
Dichloroacetate stimulates changes in the mitochondrial network morphology via partial mitophagy in human SH-SY5Y neuroblastoma cells.
Ježek et al., Praha, Czech Republic. In Int J Oncol, 2014
Samples were analyzed for cell viability, mtDNA copy number, mitochondrial network morphology and expression of key proteins involved in mitochondrial dynamics, such as LC3b, FIS1, OPA1, PARKIN and PINK1.
Inhibition of peroxisome fission, but not mitochondrial fission, increases yeast chronological lifespan.
van der Klei et al., Groningen, Netherlands. In Cell Cycle, 2014
It has been suggested that mitochondrial fragmentation, mediated by the Dnm1/Fis1 organelle fission machinery, stimulates aging and cell death.
Tracking the best reference genes for RT-qPCR data normalization in filamentous fungi.
Parrou et al., Toulouse, France. In Bmc Genomics, 2014
This group included ubcB, sac7, fis1 and sarA genes, as well as TFC1 and UBC6 that were previously validated for their use in S. cerevisiae.
Expression profile of genes modulated by Aloe emodin in human U87 glioblastoma cells.
Yusoff et al., Malaysia. In Asian Pac J Cancer Prev, 2013
SHARPIN, BCAP31, FIS1, RAC1 and TGM2 from the apoptotic cluster were confirmed by quantitative real-time PCR (qRT-PCR).
Identification of a DNA methylation-independent imprinting control region at the Arabidopsis MEDEA locus.
Grossniklaus et al., Zürich, Switzerland. In Genes Dev, 2012
imprinted MEA expression mediated by this ICR is independent of DME and MET1, consistent with the lack of any significant DNA methylation in this region
Dynamic changes of mitochondrial fission proteins after transient cerebral ischemia in mice.
Abe et al., Okayama, Japan. In Brain Res, 2012
The present study suggests a progressive activation of mitochondrial fission proteins Fis1 and phosphorylated-Drp1 after transient cerebral ischemia
miR-484 regulates mitochondrial network through targeting Fis1.
Li et al., Beijing, China. In Nat Commun, 2011
miR-484 attenuate Fis1 and mitochondrial fission by binding to N-terminal of Fis1 and inhibiting its translation.
The 1.75 Å resolution structure of fission protein Fis1 from Saccharomyces cerevisiae reveals elusive interactions of the autoinhibitory domain.
Hill et al., Baltimore, United States. In Acta Crystallogr Sect F Struct Biol Cryst Commun, 2011
1.75 A resolution crystal structure of the Fis1 cytoplasmic domain from Saccharomyces cerevisiae is reported which adopts a tetratricopeptide-repeat fold
Charcot-Marie-Tooth-related gene GDAP1 complements cell cycle delay at G2/M phase in Saccharomyces cerevisiae fis1 gene-defective cells.
Palau et al., Valencia, Spain. In J Biol Chem, 2011
Charcot-Marie-Tooth-related gene GDAP1 complements cell cycle delay at G2/M phase in Saccharomyces cerevisiae fis1 gene-defective cells
OPA1 (dys)functions.
Belenguer et al., Toulouse, France. In Semin Cell Dev Biol, 2010
DRP1 and FIS1 control mitochondrial outer membrane fission and Mitofusins its fusion.
Dynamics of peroxisome abundance: a tale of division and proliferation.
Hu et al., East Lansing, United States. In Curr Opin Plant Biol, 2009
These include the PEROXIN11 (PEX11) family, the dynamin-related proteins (DRPs), and the FISSION1 (FIS1) proteins, some of which are shared by the division machineries of peroxisomes and other organelles.
Mitochondrial reticulum network dynamics in relation to oxidative stress, redox regulation, and hypoxia.
Plecitá-Hlavatá et al., Praha, Czech Republic. In Int J Biochem Cell Biol, 2009
Here we overview the main properties and regulation of pro-fusion and pro-fission mitodynamins, i.e. dynamins-related GTPases responsible for mitochondrial shape-forming, such as pro-fusion mitofusins MFN1, MFN2, and the inner membrane-residing long OPA1 isoforms, and pro-fission mitodynamins FIS1, MFF, and DRP1 multimers required for scission.
Mitochondrial-morphology-targeted breeding of industrial yeast strains for alcohol fermentation.
Kitagaki, Saga, Japan. In Biotechnol Appl Biochem, 2009
Furthermore, it has been revealed that Fis1 [fission 1 (mitochondrial outer membrane) homologue (Saccharomyces cerevisiae)], which is a transmembrane protein with its C-terminal anchor embedded in the outer membrane of mitochondria, is required for fragmentation of yeast mitochondria during sake brewing.
Shared components of mitochondrial and peroxisomal division.
Schrader, Marburg an der Lahn, Germany. In Biochim Biophys Acta, 2006
Recent studies have led to the surprising finding that both organelles share components of their division machinery, namely the dynamin-related protein DLP1/Drp1 and hFis1, which recruits DLP1/Drp1 to the organelle membranes.
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