[The Hypereosinophilic Syndromes in Childhood].
Bern, Switzerland. In Klin Padiatr, Nov 2015
While for some subgroups of the HESN (among others FIP1L1-PDGFRA fusion gene) the administration of a tyrosine kinase inhibitor is a new and effective therapy option, glucocorticoids still represent the medication of first choice for many not PDGFRA associated variants.
Diagnostic complexities of eosinophilia.
Chapel Hill, United States. In Arch Pathol Lab Med, 2013
Most notably, chromosomal rearrangements, such as FIP1L1-PDGFRA fusions caused by internal deletions in chromosome 4, are now known to be associated with many chronic eosinophilic leukemias.