The Extracellular Matrix in Breast Cancer.
Heidelberg, Germany. In Adv Drug Deliv Rev, Jan 2016
Matrix proteins that are induced in breast cancer include fibrillar collagens, fibronectin, specific laminins and proteoglycans as well as matricellular proteins.
Fibronectin-targeted drug delivery in cancer.
Montréal, Canada. In Adv Drug Deliv Rev, Dec 2015
Alternative splicing of the precursor mRNA, produced from the single copy fibronectin gene, occurs at three sites coding for the EDA, EDB and IIICS domains.
Extracellular matrix assembly: a multiscale deconstruction.
San Francisco, United States. In Nat Rev Mol Cell Biol, 2014
The molecules that are associated with the ECM of each tissue, including collagens, proteoglycans, laminins and fibronectin, and the manner in which they are assembled determine the structure and the organization of the resultant ECM.
Accentuating and Opposing Factors Leading to Development of Thoracic Aortic Aneurysms Not Due to Genetic or Inherited Conditions.
Vancouver, Canada. In Front Cardiovasc Med, 2014
The major inhibitors or factors opposing TAA development are the constituents of the aortic wall (elastic lamellae, collagen, fibulins, fibronectin, proteoglycans, and vascular smooth muscle cells), which maintain normal aortic dimensions in the face of aortic wall stress, specific tissue MMP inhibitors, plasminogen activator inhibitor-1, protease nexin-1, and Syndecans.
Role of Irisin on the bone-muscle functional unit.
Bari, Italy. In Bonekey Rep, 2014
Irisin was originally recognized as a hormone-like myokine secreted as a product of fibronectin type III domain containing 5 from skeletal muscle in response to exercise both in mice and humans.
Rigidity sensing and adaptation through regulation of integrin types.
More papers using
London, United Kingdom. In Nat Mater, 2014
Cell binding to fibronectin through either α5β1 integrins (constitutively expressed) or αvβ6 integrins (selectively expressed in cancer and development) adapts force generation, actin flow and integrin recruitment to rigidities associated with healthy or malignant tissue, respectively.
Optical tweezers for single cells
In Annals of Biomedical Engineering, 2007
... For experiments, cells were plated on glass coverslips coated with human plasma fibronectin (Milipore Corp.) at various dilutions ... Rac and Rap GTPase activation assays.
In PLoS ONE, 2006
... Cytocholasin B (1 µg/ml), nocodazole (10 nM), MTT (0.5 mg/ml), DAPI (1 µg/ml), PMA (100 ng/ml), fibronectin (10 µg/ml), human placenta collagen type VI (10 µg/ml) and rhodamine phalloidin were from Sigma Aldrich (St ... Efficient expression system of human recombinant laminin-5.
In PLoS ONE, 2001
... from EPITOMICS; Affinity purified rabbit anti-rat IgG from Vector Laboratories (Burlingame, CA); Purified human plasma fibronectin from Millipore; rat tail type I collagen from BD Transduction Laboratories; 3,3′-dithiobis[sulfosuccinimidylpropionate] (DTSSP) cross-linker from Thermo Scientific (Rockford, IL); and, Alexa ... Cell senescence and cancer
In International Journal of Oral Science, 2000
... Glostrup, Denmark), anti-laminin 1 (1∶60; Sigma Chemical Co.), anti-laminin 5 (1∶300; Chemicon International, Temecula, CA, USA) and anti-fibronectin (1∶400; Dako S/A) ...