Extracellular Matrix Structure.
Pátrai, Greece. In Adv Drug Deliv Rev, 09 Dec 2015
UNASSIGNED: Extracellular matrix (ECM) is a non-cellular three-dimensional macromolecular network composed of collagens, proteoglycans/glycosaminoglycans, elastin, fibronectin, laminins, and several other glycoproteins.
Pharmacology of the cell/matrix form of adhesion.
Milano, Italy. In Pharmacol Res, 30 Nov 2015
I will focus on the cell/integrin form based on two specific integrins, α5β1 (the most important) and αvβ3, activated by the preferential binding of fibronectin, a unique extracellular matrix protein.
Extracellular matrix assembly: a multiscale deconstruction.
San Francisco, United States. In Nat Rev Mol Cell Biol, Dec 2014
The molecules that are associated with the ECM of each tissue, including collagens, proteoglycans, laminins and fibronectin, and the manner in which they are assembled determine the structure and the organization of the resultant ECM.
Rigidity sensing and adaptation through regulation of integrin types.
More papers using
London, United Kingdom. In Nat Mater, Jun 2014
Cell binding to fibronectin through either α5β1 integrins (constitutively expressed) or αvβ6 integrins (selectively expressed in cancer and development) adapts force generation, actin flow and integrin recruitment to rigidities associated with healthy or malignant tissue, respectively.
Optical tweezers for single cells
In Annals of Biomedical Engineering, 2007
... For experiments, cells were plated on glass coverslips coated with human plasma fibronectin (Milipore Corp.) at various dilutions ... Rac and Rap GTPase activation assays.
In PLoS ONE, 2006
... Cytocholasin B (1 µg/ml), nocodazole (10 nM), MTT (0.5 mg/ml), DAPI (1 µg/ml), PMA (100 ng/ml), fibronectin (10 µg/ml), human placenta collagen type VI (10 µg/ml) and rhodamine phalloidin were from Sigma Aldrich (St ... Efficient expression system of human recombinant laminin-5.
In PLoS ONE, 2001
... from EPITOMICS; Affinity purified rabbit anti-rat IgG from Vector Laboratories (Burlingame, CA); Purified human plasma fibronectin from Millipore; rat tail type I collagen from BD Transduction Laboratories; 3,3′-dithiobis[sulfosuccinimidylpropionate] (DTSSP) cross-linker from Thermo Scientific (Rockford, IL); and, Alexa ... Cell senescence and cancer
In International Journal of Oral Science, 2000
... Glostrup, Denmark), anti-laminin 1 (1∶60; Sigma Chemical Co.), anti-laminin 5 (1∶300; Chemicon International, Temecula, CA, USA) and anti-fibronectin (1∶400; Dako S/A) ...