Vaccines targeting self-antigens: mechanisms and efficacy-determining parameters.
Uppsala, Sweden. In Faseb J, 13 May 2015
UNASSIGNED: We recently showed that it is possible to compromise tumor vessel function and, as a consequence, suppress growth of aggressive preclinical tumors by immunizing against the tumor vascular markers extra domain-A (ED-A) or -B (ED-B) of fibronectin, using a fusion protein consisting of the ED-A or ED-B peptide fused to bacterial thioredoxin.
Extracellular matrix assembly: a multiscale deconstruction.
San Francisco, United States. In Nat Rev Mol Cell Biol, Dec 2014
The molecules that are associated with the ECM of each tissue, including collagens, proteoglycans, laminins and fibronectin, and the manner in which they are assembled determine the structure and the organization of the resultant ECM.
Use of umbilical cord serum in ophthalmology.
Kwangju, South Korea. In Chonnam Med J, Dec 2014
Like peripheral blood serum, umbilical cord blood serum contains a high concentration of essential tear components, growth factors, neurotrophic factors, vitamin A, fibronectin, prealbumin, and oil.
Rigidity sensing and adaptation through regulation of integrin types.
More papers using
London, United Kingdom. In Nat Mater, Jun 2014
Cell binding to fibronectin through either α5β1 integrins (constitutively expressed) or αvβ6 integrins (selectively expressed in cancer and development) adapts force generation, actin flow and integrin recruitment to rigidities associated with healthy or malignant tissue, respectively.
Optical tweezers for single cells
In Annals of Biomedical Engineering, 2007
... For experiments, cells were plated on glass coverslips coated with human plasma fibronectin (Milipore Corp.) at various dilutions ... Rac and Rap GTPase activation assays.
In PLoS ONE, 2006
... Cytocholasin B (1 µg/ml), nocodazole (10 nM), MTT (0.5 mg/ml), DAPI (1 µg/ml), PMA (100 ng/ml), fibronectin (10 µg/ml), human placenta collagen type VI (10 µg/ml) and rhodamine phalloidin were from Sigma Aldrich (St ... Efficient expression system of human recombinant laminin-5.
In PLoS ONE, 2001
... from EPITOMICS; Affinity purified rabbit anti-rat IgG from Vector Laboratories (Burlingame, CA); Purified human plasma fibronectin from Millipore; rat tail type I collagen from BD Transduction Laboratories; 3,3′-dithiobis[sulfosuccinimidylpropionate] (DTSSP) cross-linker from Thermo Scientific (Rockford, IL); and, Alexa ... Cell senescence and cancer
In International Journal of Oral Science, 2000
... Glostrup, Denmark), anti-laminin 1 (1∶60; Sigma Chemical Co.), anti-laminin 5 (1∶300; Chemicon International, Temecula, CA, USA) and anti-fibronectin (1∶400; Dako S/A) ...