Expression of FGFs during early mouse tongue development.
San Francisco, United States. In Gene Expr Patterns, Jan 2016
During this period, Fgf5, Fgf6, Fgf7, Fgf9, Fgf10, Fgf13, Fgf15, Fgf16 and Fgf18 could all be detected with various intensities in the mesenchyme, whereas Fgf1 and Fgf2 were expressed in both the epithelium and the mesenchyme.
Implications of Fibroblast growth factor/Klotho system in glucose metabolism and diabetes.
Santa Cruz de Tenerife, Spain. In Cytokine Growth Factor Rev, Jan 2016
More specifically, FGF19 and FGF21 signaling pathways have been linked to different glucose metabolic processes, including hepatic glucose synthesis, glycogen synthesis, glucose uptake, and insulin sensitivity, among others, and these molecules have been further related to the pathophysiology of diabetes mellitus.
Endocrine FGFs: Evolution, Physiology, Pathophysiology, and Pharmacotherapy.
Kyoto, Japan. In Front Endocrinol (lausanne), 2014
In contrast, endocrine FGFs, comprising FGF19, FGF21, and FGF23, require α-Klotho or β-Klotho as a cofactor for FGFRs.
Another Shp on the horizon for bile acids.
Lausanne, Switzerland. In Cell Metab, 2014
In this issue, research from the Feng lab reports Shp2 as a novel integrator of hepatic bile acid and FGF15/FGF19 signaling, adding another layer of complexity to the control of bile acid biosynthesis.
Physiology of FGF15/19.
United States. In Adv Exp Med Biol, 2011
Mouse Fgf15 and human FGF19 play key roles in enterohepatic signaling, regulation of liver bile acid biosynthesis, gallbladder motility and metabolic homeostasis