Coat variation in the domestic dog is governed by variants in three genes.
Bethesda, United States. In Science, 2009
Taking advantage of both inter- and intrabreed variability, we identified distinct mutations in three genes, RSPO2, FGF5, and KRT71 (encoding R-spondin-2, fibroblast growth factor-5, and keratin-71, respectively), that together account for most coat phenotypes in purebred dogs in the United States.
Genome-wide association study identifies eight loci associated with blood pressure.
Boston, United States. In Nat Genet, 2009
We identified association between systolic or diastolic blood pressure and common variants in eight regions near the CYP17A1 (P = 7 × 10(-24)), CYP1A2 (P = 1 × 10(-23)), FGF5 (P = 1 × 10(-21)), SH2B3 (P = 3 × 10(-18)), MTHFR (P = 2 × 10(-13)), c10orf107 (P = 1 × 10(-9)), ZNF652 (P = 5 × 10(-9)) and PLCD3 (P = 1 × 10(-8)) genes.
[Hair growth effect of minoxidil].
Saitama, Japan. In Nihon Yakurigaku Zasshi, 2002
On the other hand, negative factors, like FGF-5, thrombospondin, or still unknown ones, terminate the anagen phase.
Technology evaluation: gene therapy (FGF-5), Vical.
Los Angeles, United States. In Curr Opin Mol Ther, 1999
Vical has obtained preclinical data in animal models showing that a gene for a potent growth factor, FGF-5, can be delivered and expressed in coronary arteries stimulating the formation of new blood vessels.
Development of the neuromuscular junction: genetic analysis in mice.
Saint Louis, United States. In J Physiol Paris, 1998
Here, we review our studies on neuromuscular development in mutant mice lacking agrin alpha CGRP, rapsyn, MuSK, dystrophin, dystrobrevin, utrophin, laminin alpha 5, laminin beta 2, collagen alpha 3 (IV), the acetylcholine receptor epsilon subunit, the collagenous tail of acetylcholinesterase, fibroblast growth factor-5, the neural cell adhesion molecule, and tenascin-C.