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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

FEV

FEV, PET1
This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on FEV
Region-specific regulation of 5-HT1A receptor expression by Pet-1-dependent mechanisms in vivo.
GeneRIF
Albert et al., Ottawa, Canada. In J Neurochem, 2011
The data of this study indicated that, in addition to transcriptional regulation by Pet-1 in raphe neurons, 5-HT1A receptor expression is regulated indirectly by alterations in 5-HT neurotransmission in a region-specific manner
A genetically defined morphologically and functionally unique subset of 5-HT neurons in the mouse raphe nuclei.
GeneRIF
Gaspar et al., Paris, France. In J Neurosci, 2011
Pet1-dependent and Pet1-resistant 5-serotonin (5-HT) neurons target different brain centers that might delineate the anatomical basis for a dual serotonergic control on stress responses.
Pet-1 is required across different stages of life to regulate serotonergic function.
GeneRIF
Deneris et al., Cleveland, United States. In Nat Neurosci, 2010
This study indicated that Pet-1 is required across the lifespan of the mouse and that behavioral pathogenesis can result from both developmental and adult-onset alterations in serotonergic transcription.
The expression of the transcription factor FEV in adult human brain and its association with affective disorders.
GeneRIF
Schmitt et al., W├╝rzburg, Germany. In J Neural Transm, 2010
our data argue against an exclusive role of FEV in the adult human brain serotonergic system and genetic analyses did not suggest that FEV variation adds to the genetic liability towards affective disorders
Bradycardia in serotonin-deficient Pet-1-/- mice: influence of respiratory dysfunction and hyperthermia over the first 2 postnatal weeks.
GeneRIF
Nattie et al., United States. In Am J Physiol Regul Integr Comp Physiol, 2010
Pet-1(-/-) neonates are probably not hypoxic from respiratory dysfunction until P14-15; neither apnea-related hypoxia nor greater hypopnea contribute to the enhanced bradycardias of Pet-1 and there may be enhanced temperature reflex in hyperthermia
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