GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 19 Dec 2016.
Fetuin B
fetuin-B, 16 G2, GUGU
The protein encoded by this gene is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and response to systemic inflammation. This protein may be secreted by cells. [provided by RefSeq, Jul 2008] (from
NCBI)
Sponsored links
Top mentioned proteins:
CD45, CAN, ACID, fetuin-A, Serum albumin
Papers on
fetuin-B
Association of high fetuin-B concentrations in serum with fertilization rate in IVF: a cross-sectional pilot study.
New
Aachen, Germany. In Hum Reprod, Feb 2016
STUDY QUESTION: Is serum fetuin-B associated with the fertilization rate in in vitro fertilization (IVF)?
Fetuin B Is a Secreted Hepatocyte Factor Linking Steatosis to Impaired Glucose Metabolism.
New
Impact
Australia. In Cell Metab, Jan 2016
Targeted analysis showed that fetuin B was increased in humans with liver steatosis and patients with type 2 diabetes.
Population-specific plasma proteomes of marine and freshwater three-spined sticklebacks (Gasterosteus aculeatus).
New
Davis, United States. In Proteomics, Dec 2015
Moreover, fetuin B and leukocyte cell derived chemotaxin 2 are much more abundant in marine fish.
Circulating Transcript Analysis (NETest) in GEP-NETs Treated With Somatostatin Analogs Defines Therapy.
New
Olsztyn, Poland. In J Clin Endocrinol Metab, Nov 2015
Grading: 12 G1, 16 G2.
The serum protein fetuin-B is involved in the development of acute myocardial infarction.
New
Ch'ŏngju, South Korea. In Clin Sci (lond), Jul 2015
The expression of six proteins, including fibrinogen, fetuin-B, keratin 9, proapolipoprotein and fibrinogen, were altered in serum from patients with AMI compared with serum from those with SA.
Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology.
London, United Kingdom. In Alzheimers Dement, 2014
The strongest associations of protein levels with AD outcomes were prostate-specific antigen complexed to α1-antichymotrypsin (AD diagnosis), pancreatic prohormone (AD diagnosis, left entorhinal cortex atrophy, and left hippocampus atrophy), clusterin (rate of cognitive decline), and fetuin B (left entorhinal atrophy).
Mammalian gamete fusion depends on the inhibition of ovastacin by fetuin-B.
Review
In Biol Chem, 2014
These small amounts of protease are inactivated by the plasma protein fetuin-B, thus keeping eggs fertilizable.
Regulation of macromolecular modulators of urinary stone formation by reactive oxygen species: transcriptional study in an animal model of hyperoxaluria.
Gainesville, United States. In Am J Physiol Renal Physiol, 2014
Genes encoding for fibronectin, CD 44, fetuin B, osteopontin, and matrix-gla protein were upregulated while those encoding for heavy chains of inter-alpha-inhibitor 1, 3, and 4, calgranulin B, prothrombin, and Tamm-Horsfall protein were downregulated.
The effect of exposure to a high-fat diet on microRNA expression in the liver of blunt snout bream (Megalobrama amblycephala).
Nanjing, China. In Plos One, 2013
Six putative lipid metabolism-related target genes (fetuin-B, Cyp7a1, NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2, 3-oxoacid CoA transferase 1b, stearoyl-CoA desaturase, and fatty-acid synthase) were identified as having potential important roles in the development of diet-induced hepatic steatosis in blunt snout bream.
Identification of differential pattern of protein expression in canine osteoarthritis serum after anterior cruciate ligament transection: a proteomic analysis.
Liège, Belgium. In Vet J, 2013
Canine serum proteome mapping reveals the presence of proteins of interest, such as fetuin B, complement C3 and C1s and pregnancy zone protein.
Gender dimorphism in regulation of plasma proteins in streptozotocin-induced diabetic rats.
Taegu, South Korea. In Proteomics, 2013
In addition, for the first time, we identified several differentially regulated plasma proteins between healthy control and diabetic rats, including apolipoprotein E, fetuin B, α-1-acid glycoprotein, β-2-glycoprotein 1, 3-hydroxyanthranilate 3,4-dioxygenase, and serum amyloid P-component.
Fetuin-B, a liver-derived plasma protein is essential for fertilization.
Aachen, Germany. In Dev Cell, 2013
Here, we report that targeted gene deletion of the liver-derived plasma protein fetuin-B causes premature ZP hardening and, consequently, female infertility.
Proteomic profiling of dog urine after European adder (Vipera berus berus) envenomation by two-dimensional difference gel electrophoresis.
Helsinki, Finland. In Toxicon, 2013
From these, five proteins were identified: beta-2-microglobulin (b2MG), alpha-1-antitrypsin (AAT), albumin, fetuin-B and superoxide dismutase (SOD1).
Toxicological effects of cationic nanobubbles on the liver and kidneys: biomarkers for predicting the risk.
Taiwan. In Food Chem Toxicol, 2012
According to plasma proteomic profiles, gelsolin and fetuin-B were significantly downregulated 3-fold in the high-dose SME-treated group.
Downregulation of fetuin-B and zinc-α2-glycoprotein is linked to impaired fatty acid metabolism in liver cells.
GeneRIF
Taegu, South Korea. In Cell Physiol Biochem, 2011
Reduced expression of fetuin-b led to a significant increase in the expression of lipogenic genes, thereby resulting in higher lipid levels.
Type 3 cystatins; fetuins, kininogen and histidine-rich glycoprotein.
Review
Uppsala, Sweden. In Front Biosci, 2008
This review describes the properties of four structurally related, abundant plasma proteins denoted fetuin-A/alpha-2-Heremans Schmid-glycoprotein (AHSG), fetuin-B (FETUB), kininogen (KNG) and histidine-rich glycoprotein (HRG).
Renal osteodystrophy: alpha-Heremans Schmid glycoprotein/fetuin-A, matrix GLA protein serum levels, and bone histomorphometry.
GeneRIF
Roma, Italy. In Am J Kidney Dis, 2006
results support the hypothesis that fetuin-A serum levels are associated with bone cell activity
Processing and transport of matrix gamma-carboxyglutamic acid protein and bone morphogenetic protein-2 in cultured human vascular smooth muscle cells: evidence for an uptake mechanism for serum fetuin.
GeneRIF
Winston-Salem, United States. In J Biol Chem, 2004
serum fetuin has a role in processing and transport of matrix gamma-carboxyglutamic acid protein and bone morphogenetic protein-2 in cultured human vascular smooth muscle cells
Identification of Fetuin-B as a member of a cystatin-like gene family on mouse chromosome 16 with tumor suppressor activity.
GeneRIF
San Francisco, United States. In Genome, 2004
Overexpression of Fetuin-B in skin squamous carcinoma cells led to suppression of tumor growth in nude mice.
