Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction
In PLoS ONE, 2008
... Fbw7, Invitrogen (Carlsbad, CA); Myc, Cell Signaling Technology (Beverly, MA); Cdh1, Millipore (Billerica, MA); Fbx2, Fbxw8, Novus Biologicals (Littleton, CO); β-actin, MP ...
Genomic structural variants are linked with intellectual disability.
Moscow, Russia. In J Neural Transm, Sep 2015
19 out of 21 ID cases carried segmental CNV and 20 of 21 them displayed ROH segments with mean size lengths for ID cases 2512 kb (500-6,472 kb) and for healthy control 682 kb (531-986 kb), including the genes MED13L, HRK, FBXW8, TESC, CDK2AP1 and SBNO1.