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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

F-box and leucine-rich repeat protein 17

Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: V1a, OUT, fibrillin-1, Nrf2, CAN
Papers on FBXL17
RTN4 and FBXL17 Genes are Associated with Coronary Heart Disease in Genome-Wide Association Analysis of Lithuanian Families.
Kučinskas et al., Vilnius, Lithuania. In Balkan J Med Genet, 2013
Two SNPs (rs17046570 in the RTN4 gene and rs11743737 in the FBXL17 gene) stood out and may prove to be important genetic factors for CHD risk.
Breast cancer association studies in a Han Chinese population using 10 European-ancestry-associated breast cancer susceptibility SNPs.
Li et al., Guangzhou, China. In Asian Pac J Cancer Prev, 2013
METHODS: Ten SNPs (rs2075555 in COL1A1, rs12652447 in FBXL17, rs10941679 in 5p12/MRPS30, rs11878583 in ZNF577, rs7166081 in SMAD3, rs16917302 in ZNF365, rs311499 in 20q13.3,
Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.
Harper et al., Boston, United States. In Mol Cell, 2013
In validation experiments, we identify the unstudied F-box protein FBXL17 as a regulator of the NFR2 oxidative stress pathway.
Identification of F-box/LLR-repeated protein 17 as potential useful biomarker for breast cancer therapy.
Yen et al., Duarte, United States. In Cancer Genomics Proteomics, 2008
F-box protein 17 (FBXL17) can serve as a therapeutic target and surrogate marker for breast cancer therapy.
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