The effect of insulin on plasma glucose concentrations, expression of hepatic glucose transporters and key gluconeogenic enzymes during the perinatal period in broiler chickens.
Leuven, Belgium. In Gen Comp Endocrinol, Jan 2016
However, little is known about the response of insulin on plasma glucose concentrations and mRNA abundance of hepatic glucose transporters 1, 2, 3, 8, 9 and 12 (GLUT 1, 2, 3, 8, 9 and 12) and three regulatory enzymes of the gluconeogenesis, phosphoenolpyruvate carboxykinase 1 and 2 (PCK 1 and 2) or fructose-1,6-biphosphatase 1 (FBP1) in chicks during the perinatal period.
An RNA interference screen identifies new avenues for nephroprotection.
Buffalo, United States. In Cell Death Differ, Dec 2015
We used an RNA interference screen to identify genes (BCL2L14, BLOC1S2, C2ORF42, CPT1A, FBP1, GCNT3, RHOB, SCIN, TACR1, and TNFAIP6) whose suppression improves survival of kidney epithelial cells in in vitro models of oxygen and glucose deprivation.
Alteration of factors associated with hepatic gluconeogenesis in response to acute lipopolysaccharide in dairy goat.
In J Anim Sci, Jun 2015
In liver tissue, the mRNA of key gluconeogenic enzymes, phosphoenolpyruvate carboxykinase 1 (PEPCK1;P < 0.05), fructose-1,6-bisphosphatase 1 (FBP1;P < 0.01), pyruvate carboxylase (PCB;P < 0.05), and acyl-CoA synthetase short-chain family member 3 (ACSS3; < 0.01), in the related pathways and PPAR-γ coactivator 1α (PGC-1α;P < 0.05) were decreased in the LPS group compared with those in the control group, whereas glucose-6-phosphatase (G6Pase-α) was not different (P > 0.05).
Fructose-1,6-bisphosphatase opposes renal carcinoma progression.
Philadelphia, United States. In Nature, 2014
Here we used an integrative approach comprising pan-metabolomic profiling and metabolic gene set analysis and determined that the gluconeogenic enzyme fructose-1,6-bisphosphatase 1 (FBP1) is uniformly depleted in over six hundred ccRCC tumours examined.
Host factors in enterovirus 71 replication.
Taiwan. In J Virol, 2011
Three of these proteins, heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1), far-upstream element-binding protein 2 (FBP2), and FBP1 are nuclear proteins which in EV71-infected cells are relocalized to the cytoplasm, and they influence EV71 internal ribosome entry site (IRES) activity.
The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation.
London, United Kingdom. In Cell Signal, 2004
In recent years, AREs have shown to be binding sites for numerous proteins including HuR, TTP, AUF1, AUF2, FBP1, FBP2 (KSRP), TIA-1, and TIAR.