BRI2 and BRI3 are functionally distinct phosphoproteins.
Aveiro, Portugal. In Cell Signal, Jan 2016
The functional significance of these complexes is apparent given that both BRI proteins are substrates of PP1, thus simultaneously this is the first report of BRI2 and BRI3 as phosphoproteins.
Role of BRI2 in dementia.
Amsterdam, Netherlands. In J Alzheimers Dis, 2013
Similarly, FBD and FDD originate from mutations in the BRI2 gene (or ITM2b), causing amyloid angiopathy and neurofibrillary tangles analogous to those observed in AD.
Modeling familial British and Danish dementia.
Indianapolis, United States. In Brain Struct Funct, 2010
Familial British dementia (FBD) and familial Danish dementia (FDD) are two autosomal dominant neurodegenerative diseases caused by mutations in the BRI ( 2 ) gene.