FASTKD2 is associated with memory and hippocampal structure in older adults.
Indianapolis, United States. In Mol Psychiatry, Oct 2015
Using a genome-wide screen, we discovered a novel association of a polymorphism in the pro-apoptotic gene FASTKD2 (fas-activated serine/threonine kinase domains 2; rs7594645-G) with better memory performance and replicated this finding in independent samples.
The AP-2alpha transcription factor regulates tumor cell migration and apoptosis.
Torino, Italy. In Adv Exp Med Biol, 2006
By performing a whole genome microarray analysis of the tumor cells expressing AP-2alpha siRNA, we identified several AP-2alpha-regulated genes involved in apoptosis and migration such as FAST kinase, osteopontin, caspase 9, members of the TNF family, laminin alpha 1, collagen type XII, alpha 1, and adam.