Functional interactions of APP with the apoE receptor family.
Washington, D.C., United States. In J Neurochem, 2008
A number of APP-interacting proteins have been identified: intracellularly, APP interacts with adaptor proteins through its conserved NPXY domain; extracellularly, APP interacts with a component of the extracellular matrix, F-spondin.
Regulated proteolysis of APP and ApoE receptors.
Washington, D.C., United States. In Mol Neurobiol, 2008
Binding of APP and apoE receptors to specific extracellular matrix proteins (F-spondin and Reelin) promotes their presence on the cell surface and influences whether they will interact with specific cytoplasmic adaptor proteins.