Desmoplastic Melanoma: An Updated Immunohistochemical Analysis of 40 cases with a Proposal for an Additional Panel of Stains for Diagnosis.
Milwaukee, United States. In J Cutan Pathol, Jan 2016
The purpose of this study was to analyze 40 cases of DM with a comprehensive panel of immunohistochemical markers (KBA.62, p16, Ezrin, WT-1, MITF-1, SOX-10, CD117, SOX-2, Nestin, PNL2, p75, MART-1, gp100 and S100p) to obtain a more complete understanding of the potential use of these antibodies in the diagnosis of DM.
New insights in regulation of calcium homeostasis.
Los Angeles, United States. In Curr Opin Nephrol Hypertens, 2013
Ezrin, a cross-linking protein important for renal phosphate handling, is also involved in the regulation of intestinal calcium absorption.
Rap2A links intestinal cell polarity to brush border formation.
Utrecht, Netherlands. In Nat Cell Biol, 2012
The subsequent recruitment of phospholipase D1 allows polarized accumulation of phosphatidic acid, which provides a local cue for successive signalling by the guanine nucleotide exchange factor PDZGEF, the small G protein Rap2A, its effector TNIK, the kinase MST4 and, ultimately, the actin-binding protein Ezrin.
Ezrin...a metastatic detERMinant?
United States. In Cancer Cell, 2004
Mounting evidence, culminating in the work described in two recent articles, strongly suggests that the membrane:cytoskeleton organizer Ezrin can promote tumor metastasis.