Regulation and functions of bacterial PNPase.
Milano, Italy. In Wiley Interdiscip Rev Rna, Feb 2016
UNASSIGNED: Polynucleotide phosphorylase (PNPase) is an exoribonuclease that catalyzes the processive phosphorolytic degradation of RNA from the 3'-end.
Surprises in the 3'-end: 'U' can decide too!
Lisbon, Portugal. In Febs J, Sep 2015
Namely, Dis3L2 is a 3'-5' exoribonuclease from the RNase II/RNB family that has been shown to act preferentially on oligo(U)-tailed transcripts.
Functional non-coding RNAs derived from the flavivirus 3' untranslated region.
Brisbane, Australia. In Virus Res, Sep 2015
In this review we summarize published data from studies with WNV, YFV, DENV, JEV, and MVEV on sfRNA production following incomplete degradation of the viral genomic RNA by the cellular 5'-3' exoribonuclease 1 (XRN1), RNA structural elements involved in stalling XRN1 to generate sfRNA, and functions of sfRNA in modulating cellular mRNA decay and RNAi pathways as well as in modulating anti-viral type I interferon response.