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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Even-skipped homeobox 2

EVX2
This gene is located at the 5' end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox transcription factor that is related to the protein encoded by the Drosophila even-skipped (eve) gene, a member of the pair-rule class of segmentation genes. A 117 kb microdeletion at the 5' end of the HOXD gene cluster, which includes this gene and the HOXD9-HOXD13 genes, causes synpolydactyly, a dominantly inherited disease resulting in limb malformation. [provided by RefSeq, Sep 2009] (from NCBI)
Papers on EVX2
Evx2-Hoxd13 intergenic region restricts enhancer association to Hoxd13 promoter.
GeneRIF
Kondo et al., Wako, Japan. In Plos One, 2006
Data show that the intergenic region between Evx2 and Hoxd13 behaves as a boundary element that functions differentially in space and time, specifically in the development of limbs, genital bud, and brain.
A 117-kb microdeletion removing HOXD9-HOXD13 and EVX2 causes synpolydactyly.
GeneRIF
Scambler et al., London, United Kingdom. In Am J Hum Genet, 2002
117-kb microdeletion removing HOXD9-HOXD13 and EVX2 causes synpolydactyly
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