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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Immediate early response 2

ETR101, IER2
Top mentioned proteins: AP-1, CAN, Egr-1, Fos, V1a
Papers on ETR101
Immediate-early response 5 (IER5) interacts with protein phosphatase 2A and regulates the phosphorylation of ribosomal protein S6 kinase and heat shock factor 1.
New
Sakurai et al., Kanazawa, Japan. In Febs Lett, Dec 2015
Immediate-early response 5 (IER5) is a growth factor-inducible protein with homology to the N-terminus of IER2.
Identification of immediate early response protein 2 as a regulator of angiogenesis through the modulation of endothelial cell motility and adhesion.
New
Shen et al., Yangzhou, China. In Int J Mol Med, Oct 2015
Human immediate early response 2 (IER2) has been characterized as a putative nuclear protein that functions as a transcription factor or transcriptional co‑activator in the regulation of cellular responses, and may be involved in the regulation of tumor progression and metastasis.
miR-30c negatively regulates the migration and invasion by targeting the immediate early response protein 2 in SMMC-7721 and HepG2 cells.
Shen et al., Yangzhou, China. In Am J Cancer Res, 2014
In this study, we demonstrated that over-expression and knockdown of immediate early response protein 2 (IER2) modulated the general capacity of the migration and invasion in hepatocellular carcinoma cell line SMMC-7721 and HepG2, whereas overexpression and knockdown of miR-30c decreased and promoted cell motility, respectively.
Twenty-Four Genes are Upregulated in Patients with Hypospadias.
Basaklar et al., Ankara, Turkey. In Balkan J Med Genet, 2013
Other genes that have not been previously reported were also found to be upregulated: BTG2, CD69, CD9, DUSP1, EGR1, EIF4A1, FOS, FOSB, HBEGF, HNRNPUL1, IER2, JUN, JUNB, KLF2, NR4A1, NR4A2, PTGS2, RGS1, RTN4, SLC25A25, SOCS3 and ZFP36 (p <0.05).
The immediate early gene Ier2 promotes tumor cell motility and metastasis, and predicts poor survival of colorectal cancer patients.
GeneRIF
Sleeman et al., Karlsruhe, Germany. In Oncogene, 2012
ectopic Ier2 expression promoted the motility and invasiveness of poorly metastatic 1AS pancreatic tumor cells in vitro
XIer2 is required for convergent extension movements during Xenopus development.
Dawid et al., Bethesda, United States. In Int J Dev Biol, 2010
Immediate early response 2 (Ier2) is a downstream target of fibroblast growth factor (FGF) signaling.
Functional analyses of immediate early gene ETR101 expressed in yeast.
GeneRIF
Nikawa et al., Fukuoka, Japan. In Biosci Biotechnol Biochem, 2009
the functioning of ETR101 as a transcriptional activator for the gene ISYNA1
FGF-dependent left-right asymmetry patterning in zebrafish is mediated by Ier2 and Fibp1.
GeneRIF
Dawid et al., Bethesda, United States. In Proc Natl Acad Sci U S A, 2009
Ier2 and Fibp1 mediate FGF signaling in ciliogenesis in Kupffer's Vesicle and in the establishment of laterality in the zebrafish embryo
Influence of surgical manipulation on prostate gene expression: implications for molecular correlates of treatment effects and disease prognosis.
Impact
Nelson et al., Seattle, United States. In J Clin Oncol, 2006
These included transcripts encoding acute phase response proteins, IER2 and JUNB, and regulators of cell proliferation, p21Cip1 and KLF6.
Gene profiling involved in immature CD4+ T lymphocyte responsible for systemic lupus erythematosus.
Hao et al., Anqing, China. In Mol Immunol, 2006
The genes functions were related to a diverse cellular process including: (1) most of these genes were associated with CD4+ T cells functions, particularly related to cellular developments; (2) Ras pathway genes as RANBP10, GMIP, RASGRP2 and ARL5 might be responsible for the abnormal development of CD4+ T cells of SLE; (3) HIG2, TCF7, KHSRP, WWP1, SMAD3, TLK2, AES, CCNI and PIM2 belong to Wnt/beta-catenin way, they could play roles in modulating proliferation and differentiation of T lymphocytes; (4) uncertain viral infections may initiate autoimmunity because high levels expression genes were detected in T4-1s such as TRIM22, IER2, ABCE1, DUT, G1P2, G1P3, HNRPUL1, EVER2, IFNAR1, TNFSF14, TMP21 and PVRL2; and (5) apoptosis relating genes as EIF3S8, SH3BGRL3, GPX4, TOSO, PFDN5, BIN1, XIAPAF1, TEGT and CUGBP2 may contribute to over uploading of selfantigens in SLE cells.
Molecular characterization of Coriolus versicolor PSP-induced apoptosis in human promyelotic leukemic HL-60 cells using cDNA microarray.
Wan et al., Hong Kong, Hong Kong. In Int J Oncol, 2005
Our data show that PSP-induced apoptosis in HL-60 cells might be mediated by up-regulation of early transcription factors such as AP-1, EGR1, IER2 and IER5, and down-regulation of NF-kappaB transcription pathways.
Transcriptional activation of immediate-early gene ETR101 by human T-cell leukaemia virus type I Tax.
Liu et al., Århus, Denmark. In J Gen Virol, 2003
This study describes the finding of immediate-early gene ETR101 expression in HTLV-I-infected cells and its regulation by Tax.
Patterns of gene expressions induced by arsenic trioxide in cultured human fibroblasts.
Bergé-Lefranc et al., Marseille, France. In Toxicol Lett, 2003
In cultured human fibroblasts exposed for 24 h to micromolar arsenic concentrations, we studied, using real-time RT-PCR, the expression profile of a limited number of genes: genes coding for a stress protein (HSP70), transcription factors (cJUN, cFOS, ETR103, ETR101 and TTP) and cell cycle or DNA repair proteins (P21, GADD153).
The expression of genes induced in melanocytes by exposure to 365-nm UVA: study by cDNA arrays and real-time quantitative RT-PCR.
Botta et al., Marseille, France. In Biochim Biophys Acta, 2002
These genes included genes involved in cell cycle regulation (GADD45, CIP1/WAF1), in stress response (HSP70, HSP40, HSP86), in apoptosis (GADD153, tristetraproline) and genes encoding transcription factors (EGR-1, ETR-101, c-JUN, ATF4).
The reprogrammed host: Chlamydia trachomatis-induced up-regulation of glycoprotein 130 cytokines, transcription factors, and antiapoptotic genes.
Klos et al., Hannover, Germany. In Arthritis Rheum, 2001
RESULTS: Eighteen genes (of 1,176) were found to be up-regulated after 24 hours of infection with this obligate intracellular bacterium, among them the glycoprotein 130 family members IL-11 and LIF, the chemokine gene MIP2-alpha, the transcription factor genes EGR1, ETR101, FRA1, and c-jun, the apoptosis-related genes IEX-1L and MCL-1, adhesion molecule genes such as ICAM1, and various other functionally important genes.
Regulation of gene expression by muscarinic acetylcholine receptors.
Nitsch et al., Hamburg, Germany. In Biochem Soc Symp, 2000
These included the transcription factors Egr-1, Egr-2, Egr-3, c-Jun, Jun-D and Gos-3; the growth regulator hCyr61; the signalling factors NGFi-B (nerve growth factor induced gene-B) and Etr101; the unknown gene Gig-2 (for G-protein-coupled receptor induced gene 2); and the acetylcholinesterase gene (ACHE).
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