GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 19 Dec 2016.
Ethanolaminephosphotransferase 1
Ethanolaminephosphotransferase, Selenoprotein, Sep15, sel-1, Med8, EPT1
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008] (from
NCBI)
Top mentioned proteins:
ACID, CAN, selenoprotein P, HAD, PI3K
Papers on
Ethanolaminephosphotransferase
Se Enhances MLCK Activation by Regulating Selenoprotein T (SelT) in the Gastric Smooth Muscle of Rats.
New
Wuhan, China. In Biol Trace Elem Res, Feb 2016
Selenoprotein T (SelT) was identified as a redoxin protein with a selenocystein, localizing in the endoplasmic reticulum.
Nuclear selenoproteins and genome maintenance.
Review
New
Wenzhou, China. In Iubmb Life, Jan 2016
To date, only five selenoproteins are experimentally demonstrated to reside in nucleus, exclusively or partially, including selenoprotein H, methionine-R-sulfoxide reductase 1, glutathione peroxidase-4, thioredoxin reductase-1, and thioredoxin glutathione reductase.
Expression of Selenoprotein Genes Is Affected by Heat Stress in IPEC-J2 Cells.
New
Chengdu, China. In Biol Trace Elem Res, Jan 2016
UNASSIGNED: The aim of this study was to explore the impacts of heat stress (HS) on expressions of selenoprotein genes in IPEC-J2 cells.
Effect of Inorganic Dietary Selenium Supplementation on Selenoprotein and Lipid Metabolism Gene Expression Patterns in Liver and Loin Muscle of Growing Lambs.
New
Poland. In Biol Trace Elem Res, Jan 2016
UNASSIGNED: Effect of selenium (Se) supplementation on the selenoprotein and lipid metabolism gene expression patterns in ruminants, especially in lambs is not yet fully understood.
Effects of Dietary Selenium Against Lead Toxicity on mRNA Levels of 25 Selenoprotein Genes in the Cartilage Tissue of Broiler Chicken.
New
Nanjing, China. In Biol Trace Elem Res, Jan 2016
In detail, Se could alleviate the downtrend of the expression of Gpx1, Gpx2, Gpx4, Txnrd2, Txnrd3, Dio1, Dio2, Seli, Selu, Sepx1, Selk, Selw, Selo, Selm, Sep15, Sepnn1, Sels, and Selt induced by Pb exposure in the meniscus cartilage.
Selenoprotein expression in macrophages is critical for optimal clearance of parasitic helminth Nippostrongylus brasiliensis.
New
United States. In J Biol Chem, Jan 2016
UNASSIGNED: The plasticity of macrophages is evident in helminthic parasite infections, providing protection from inflammation.
Selenium Deficiency Mainly Influences Antioxidant Selenoproteins Expression in Broiler Immune Organs.
New
Harbin, China. In Biol Trace Elem Res, Jan 2016
UNASSIGNED: Selenoprotein has many functions in chicken, and the expression of selenoproteins is closely associated with the selenium (Se) level.
Tolerance of the foodborne pathogen Listeria monocytogenes to quaternary ammonium sanitizers is mediated by a novel efflux pump encoded by emrELm.
New
Winnipeg, Canada. In Appl Environ Microbiol, Dec 2015
LGI1 genes with putative efflux (emrELm), regulatory (lmo1851) and adhesion (sel1) functions were deleted, and the mutants were exposed to acid (HCl), cold (4°C), salt (10-20% NaCl), and quaternary ammonium-based sanitizers (QACs).
Selenoprotein K and protein palmitoylation.
Review
New
Honolulu, United States. In Antioxid Redox Signal, Nov 2015
SIGNIFICANCE: Selenoprotein K (SelK) is an endoplasmic reticulum (ER) membrane protein, and its expression is sensitive to dietary selenium levels.
The selenium content of SEPP1 versus selenium requirements in vertebrates.
Bergen, Norway. In Peerj, 2014
Selenoprotein P (SEPP1) distributes selenium (Se) throughout the body via the circulatory system.
The FOXO transcription factor DAF-16 bypasses ire-1 requirement to promote endoplasmic reticulum homeostasis.
Impact
In Cell Metab, 2014
We show that activation of the Caenorhabditis elegans transcription factor DAF-16 and its human homolog FOXO3 restore secretory protein metabolism when the UPR is dysfunctional.We show that DAF-16 establishes alternative ER-associated degradation systems that degrade misfolded proteins independently of the ER stress sensor ire-1 and the ER-associated E3 ubiquitin ligase complex sel-11/sel-1.
Nuclear-encoded factors associated with the chloroplast transcription machinery of higher plants.
Review
Shanghai, China. In Front Plant Sci, 2013
This covers several PPR proteins including CLB19, PDM1/SEL1, OTP70, and YS1 which are involved in the processing of transcripts for PEP core subunit as well as AtECB2, Prin2, SVR4-Like, and NARA5 that are also important for plastid gene expression, although their functions are unclear.
Intersection of selenoproteins and kinase signalling.
Review
Warsaw, Poland. In Biochim Biophys Acta, 2013
The small, obscure group of selenoprotein oxidoreductases and the huge clan of kinases, the workhorses of cellular signalling, are rarely discussed together.
The relationship between selenoprotein P and glucose metabolism in experimental studies.
Review
Shenyang, China. In Nutrients, 2013
Selenoprotein P (Sepp1) is central to selenium homeostasis and widely expressed in the organism.
Roles of the 15-kDa selenoprotein (Sep15) in redox homeostasis and cataract development revealed by the analysis of Sep 15 knockout mice.
GeneRIF
Boston, United States. In J Biol Chem, 2011
Cataracts resulted from an improper folding status of lens proteins caused by Sep15 deficiency.
Deficiency in the 15-kDa selenoprotein inhibits tumorigenicity and metastasis of colon cancer cells.
GeneRIF
Rockville, United States. In Cancer Prev Res (phila), 2010
These data suggest tissue specificity in the cancer-protective effects of Sep15 downregulation, which are mediated, at least in part, by influencing the cell cycle.
A large prospective study of SEP15 genetic variation, interaction with plasma selenium levels, and prostate cancer risk and survival.
GeneRIF
Boston, United States. In Cancer Prev Res (phila), 2010
This study provides evidence that SEP15 genetic variation may influence prostate cancer mortality
The Med8 mediator subunit interacts with the Rpb4 subunit of RNA polymerase II and Ace2 transcriptional activator in Schizosaccharomyces pombe.
GeneRIF
Delhi, India. In Febs Lett, 2009
Med8 mediator subunit is involved in transmitting regulatory information from Ace2 to RNA polymerase II via Rpb4.
Structure-system correlation identifies a gene regulatory Mediator submodule.
GeneRIF
München, Germany. In Genes Dev, 2008
Deletion of med8C, med18, or med20 causes similar changes in the yeast transcriptome.
Selenoprotein synthesis and side-effects of statins.
Review
Impact
Mainz, Germany. In Lancet, 2004
A negative effect of statins on selenoprotein synthesis does seem to explain many of the enigmatic effects and side-effects of statins, in particular, statin-induced myopathy.
