Choline metabolism-based molecular diagnosis of cancer: an update.
Baltimore, United States. In Expert Rev Mol Diagn, Jun 2015
Molecular causes of abnormal choline metabolism are changes in choline kinase-α, ethanolamine kinase-α, phosphatidylcholine-specific phospholipase C and -D and glycerophosphocholine phosphodiesterases, as well as several choline transporters.
Genome-wide association study for poor sperm motility in Holstein-Friesian bulls.
Olsztyn, Poland. In Anim Reprod Sci, 2014
The most significant SNP were located on chromosome 24 (rs110876480), 5 (rs110827324 and rs29011704), and 1 (rs110596818), in the close vicinity of melanocortin 4 receptor (MC4R), PDZ domain containing ring finger 4 (PDZRN4) and ethanolamine kinase 1 (ETNK1), olfactory receptor 5K3-like (LOC785875) genes, respectively.
Phospholipid homeostasis and lipotoxic cardiomyopathy: a matter of balance.
Los Angeles, United States. In Fly (austin), 2011
Fly mutants that bear perturbations in phosphatidylethanolamine (PE) biosynthesis, such as the easily-shocked (eas) mutants defective in ethanolamine kinase, incurred aberrant activation of the sterol regulatory element binding protein (SREBP) pathway, thereby causing chronic lipogenesis and cardiac steatosis that culminates in the development of lipotoxic cardiomyopathy.
Transcriptional control of genes involved in yeast phospholipid biosynthesis.
New York City, United States. In J Microbiol, 2011
Here, 22 out of 47 phospholipid biosynthetic genes were identified as UAS(INO)-containing genes, including EKI1, EPT1, INM1, IPK2, KCS1, PAH1, and PIK1 which have never been reported before.